Browse Technologies

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Adaptive PCR: A PCR control system to overcome challenging conditions

A PCR control system to overcome challenging conditions. By directly monitoring the hybridization of fluorescently labelled L-DNA mimics of the template DNA strands and primers, it is possible to improve the efficiency of PCR in challenging conditions. This approach eliminates some of the sample preparation and trial and error that would otherwise be required for difficult sample types such as urine or other samples that contain high levels of salts.  In addition, this approach enables on-demand PCR in most any environment.


Licensing Contact

Jody Hankins

615.322.5907
Research Reagent

Steerable Needles: A Better Turning Radius with Less Tissue Damage

A team of Vanderbilt engineers and surgeons have developed a new steerable needle that can make needle based biopsy and therapy delivery more accurate. A novel flexure-based tip design provides enhanced steerability while simultaneously minimizing tissue damage. The present device is useful for almost any needle-based procedure including biopsy, thermal ablation, brachytherapy, and drug delivery.


Licensing Contact

Ashok Choudhury

615.322.2503

Non-Invasive Bacterial Identification for Acute Otitis Media using Raman Spectroscopy

Real-time non-invasive Raman Sprectoscopy system to detect the presence and identity of pathogens involved in causing middle ear infections.


Licensing Contact

Ashok Choudhury

615.322.2503

Non-Invasive Skin Cancer Detection using Raman Spectroscopy-OCT System (Portfolio)

Vanderbilt University researchers have designed a system for non-invasive discrimination between normal and cancerous skin lesions. The system combines the depth-resolving capabilities of OCT technique with Raman Spectroscopy's specificity of molecular chemistry. By linking both imagining techniques into a single detector arm, the complexity, cost, and size of previously reported RS-OCT instruments have been significantly improved. The combined instrument is capable of acquiring data sets that allow for more thorough assessment of a sample than existing optical techniques.


Licensing Contact

Ashok Choudhury

615.322.2503

Systems and Methods for Optical Stimulation of Neural Tissues (Portfolio)

Vanderbilt researchers have developed a novel technique for contactless simulation of the central nervous system.  This involves the use of infrared neural stimulation (INS) to evoke the observable action potentials from neurons of the central nervous system.  While infrared neural stimulation of the peripheral nervous system was accomplished almost a decade ago, this is the first technique for infrared stimulation of the central nervous system. This technology has been protected by a portfolio of issued patents.


Licensing Contact

Ashok Choudhury

615.322.2503

MAESTRO: Non-Robotic Dexterous Laproscopic Instrument with a Wrist providing seven degrees of freedom

Inventors at Vanderbilt University have developed a non-robotic dexterous laparoscopic manipulator with a wrist providing seven-degrees-of-freedom. It provides an interface which intuitively maps motion of the surgeon's hands to the tool's ""hands"". The novel user interface approach provides a natural mapping of motion from the surgeon's hands to the instrument tips.


Licensing Contact

Ashok Choudhury

615.322.2503
Medical Devices

MultiUse Multimodal Imaging Chelates

PK11195 is a high-affinity ligand of the peripheral benzodiazepine receptor (PBR). By linking lanthanide chelates to the PK11195 targeting moiety, Vanderbilt researchers have generated a range of PBR-targeted imaging probes capable of visualizing a number of disease states at cellular levels using a variety of imaging modalities (fl uorescence, PET and SPECT, MRI, electron microscopy).


Licensing Contact

Taylor Jordan

615.936.7505
Medical Imaging

Rotary planar peristaltic micropump (RPPM) and Rotary Planar Valve (RPV) for microfluidic systems

A research team led by Professor John Wikswo of Vanderbilt University has developed a low-cost, small-volume, metering peristaltic micro pumps and microvalves. They can be either utilized as a stand-alone device, or incorporated into microfluidic subsystems for research instruments or miniaturized point-of-care instruments, Lab on a Chip devices, and disposable fluid delivery cartridges. The key advantage of this pump is that it can deliver flow rates as low as a few hundred nL/min to tens of µL/min against pressure heads as high as 20 psi, at approximately 1/10th the cost of stand-alone commercial syringe and peristaltic pumps. The RPV can implement complicated fluid control protocols and fluidic mixing without bulky pneumatic controllers. Both the RPPM and RPV can be readily optimized for particular applications.


Licensing Contact

Ashok Choudhury

615.322.2503

High Performance Battery Electrodes Using Electrospun Nanofibers

A Vanderbilt researcher has developed a new battery electrode that uses particle/polymer electrospun nanofiber mats to increase energy density and decrease the required charge time for the battery. The technique can be used with any high energy density metal-ion batteries such as lithium-ion or sodium-ion.


Licensing Contact

Philip Swaney

615.322.1067

Inventors

Peter Pintauro
Energy

Load-Bearing Energy Storage Composites from Porous Materials and Methods for Production Thereof

A team of Vanderbilt engineers has developed a multifunctional, loadbearing solid-state supercapacitor to simultaneously store energy and withstand static and dynamic mechanical stresses.


Licensing Contact

Ashok Choudhury

615.322.2503
Energy