Medical Devices

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Low-Cost Non-Invasive Handheld Ultrasound Device for Measuring Tissue Stiffness

Vanderbilt University researchers have developed a hand-held device to quantitatively measure tissue stiffness for medical monitoring. This device is non-invasive, low-cost, and can be used at the point of care.


Licensing Contact

Masood Machingal

615.343.3548

A Novel Organs-On-Chip Platform

Vanderbilt researchers have created a new multi-organs-on-chip platform that comprises Perfusion Control systems, MicroFormulators, and MicroClinical Analyzers connected via fluidic networks. The real-time combination of multiple different solutions to create customized perfusion media and the analysis of the effluents from each well are both controlled by the intelligent use of a computer-operated system of pumps and valves. This permits, for the first time, a compact, low-cost system for creating a time-dependent drug dosage profile in a tissue system inside each well.


Licensing Contact

Ashok Choudhury

615.322.2503

Novel Scaffolding Allows for More Effective Cell Transplanting

Vanderbilt researchers have bioengineered a new scaffolding that provides immediate blood flow to transplanted cells and is undetected by the immune system's lymphatic surveillance. Traditionally, transplanting tissue and cells triggers an immune attack on said cells, often causing the body to reject the transplanted matter. A major conduit for these attacks is the disruption of the lymphatic vessel "surveillance system". This novel scaffolding aims to prevent an immune attack by bypassing the surveillance.


Licensing Contact

Philip Swaney

615.322.1067

Wearable Metabolic Rate Sensor

Vanderbilt researchers have developed a portable, non-invasive sensor system that can take measurements through the skin to provide insights into metabolic rate and energy expenditure outside of a clinical setting. Existing methods for estimating metabolic rate rely on comparisons between user-reported body parameters and population averages, which can result in inaccurate estimates. Additionally, existing portable devices that provide estimates of metabolic rate are limited by factors such as cost per use and frequency of measurement. The present technology overcomes these limitations and can be directly integrated with commercial wearable devices for an accurate assessment of metabolic rate.


Licensing Contact

Philip Swaney

615.322.1067
Medical Devices

An Imaging Approach to Detect Parathyroid Gland Health During Endocrine Surgery

Vanderbilt researchers have designed a laser speckle imaging device to detect parathyroid gland viability during endocrine surgery, during which otherwise healthy parathyroid glands are prone to devascularization leading to long-term hypocalcemia. Currently, the surgeon must use his or her best judgement regarding the health of the parathyroid gland. This technology removes the guess work from the decision and provides a real-time assessment of the parathyroid viability.


Licensing Contact

Ashok Choudhury

615.322.2503
Medical Devices

Peripheral Nerve Catheter Advancer

A Vanderbilt clinician has developed a device capable of allowing a single practitioner to control both the needle and the catheter while using an ultrasound probe to place a nerve block. A nerve block involves the placement of anesthetic and other agents onto or near a nerve in order to temporarily disrupt the signal traveling along the nerve. To place a nerve block, a needle is inserted into the patient and a catheter is thread through the needle to inject the block. An ultrasound probe is used to identify placement of the catheter and nerve block. Current catheter advancement techniques require one clinician to hold the needle and control the catheter while a second person maneuvers the ultrasound probe to accurately deliver the nerve block. The proper placement of the nerve block is highly dependent on the coordination between the two individuals. Relying on a second individual can result in misplaced nerve blocks or prolong the placement process. The novel catheter advancer eliminates the need for a second clinician and makes the placement faster and more accurate.


Licensing Contact

Philip Swaney

615.322.1067
Medical Devices

Real-Time Feedback for Positioning Electrode Arrays in Cochlear Implants

Vanderbilt researchers have discovered a method ofmonitoring the placement of electrodes in cochlearimplants (CIs) through the use of electrical impedancemeasurements. This technology offers real-timefeedback on electrode positioning, which can beused to more accurately place electrodes duringinitial implantation, or better program the implantsafter they have been placed. These enhancementscombine to give increased hearing quality to bothnew and existing CI patients.


Licensing Contact

Philip Swaney

615.322.1067

Palatoglossus Muscle Stimulation for Treatment of Obstructive Sleep Apnea

A Vanderbilt researcher has developed a device to stimulate the palatoglossus muscle in order to treat sleep apnea. This has the potential to treat patients who have failed to succeed with current sleep apnea treatments.


Licensing Contact

Chris Harris

615.343.4433
Medical Devices

Closed-loop System for Adjustment of Cranial Nerve Stimulator for Obstructive Sleep Apnea

A Vanderbilt researcher has developed a closed-loop system that combines live recorded data from a polysomnography (PSG) system amplifier with output from a system providing real-time feedback on the structure of the pharyngeal airway. This would allow the system to automatically adjust a hypoglossal nerve stimulator to treat obstructive sleep apnea.


Licensing Contact

Chris Harris

615.343.4433

Inventors

David Kent
Medical Devices

Method for Non-Invasive Complete Vascular Occlusion Using MR Guided Focused Ultrasound Surgery

Researchers have developed a non-invasive method for creating vascular occlusions at specific locations within a vessel using magnetic resonance guided focused ultrasound (MRgFUS). The speed and efficacy of this approach is better than traditional vascular occlusion methods, and the method can be further enhanced through the use of phase shift nano-droplets. The approach is even applicable to large vessels that can be extremely challenging to ablate due to the heat sink effect. Ultimately, the ability to occlude selected vasculature could aid in the treatment of vascular malformations, hemorrhage control, and tumor devascularization.


Licensing Contact

Chris Harris

615.343.4433
Medical Devices