Browse Technologies

Displaying 171 - 178 of 178

Integrated Device for Leaching Extraction and Assessment

The invention is a device which permits the direct quantification of leachable organic constituents from within solid materials. It is expected that the device will be used in landfills and in other environments where measurements are central to the evaluation of the environmental compatibility of solid materials (e.g., sediments, soils, solidified waste forms) containing organic constituents that have the potential to degrade water resources of to be taken up by biota and the food chain. The invention is designed to simplify current difficulties in assessing leaching of organic constituents with low aqueous solubility.

Licensing Contact

Chris Harris

615.343.4433

Inventors

David Kosson, Leslie Shor, Andrew Garrabrants
Category:
Research Tools

Improved Piezoimmunosensor

An apparatus comprising one or more piezoelectric mass sensors for use in diagnostic and analytic processes, in particular for immunochemical detection of diagnostically relevant analytes in real time. Each piezoelectric mass sensor comprises a piezoelectric crystal with a receptor surface which has immobilized thereon a lawn of recombinant antibodies comprising single V.sub.H chain or single-chain Fv (scFv) polypeptides specific for a particular antigen. Binding of antigen to the recombinant antibodies results in a change in mass on the receptor surface which is detected as a change in resonant frequency. In a preferred embodiment, the receptor layer is a precious metal such as gold which facilitates self-assembly of the recombinant antibodies into a lawn on the receptor surface via a cysteine residue at the carboxy terminus of the attachment polypeptide.

Licensing Contact

Mike Villalobos

615.322.6751

Inventors

Raymond Mernaugh, Xiangqun Zeng, Gabrielle Stryker
Category:
Diagnostics

Heterologous Expression System for Studying Recombinant Human Brain Voltage-Gated Sodium Channel, SCN1A

Isolated nucleic acids encoding human SCN1A polypeptides, recombinantly expressed and isolated human SCN1A polypeptides, heterologous expression systems for recombinant expression of human SCN1A polypeptides, assay methods employing the same, and methods and compositions for modulation of sodium channel function.

Licensing Contact

Karen Rufus

615.322.4295

Inventors

Alfred George, Christoph Lossin
Category:
Research Tools
Research Tool Type:
Nucleic Acid/Plasmid

EP4 Transgenic Mice

EP4 Transgenic Mice are part of the Vanderbilt Research Tools Catalog.

Licensing Contact

Karen Rufus

615.322.4295

Inventors

Matthew Breyer, Youfei Guan, Andre Schneider
Category:
Research Tools
Field of Use:
Cardiovascular Inflammatory/Immune Oncology
Research Tool Type:
Animal Model

Method for the Automatic Segmentation of the Facial Nerve and the Chorda Tympani in CT Images

This is a high resolution imaging device that can detect the fundamental functional units of cortical organization. Currently, with existing technology, we are able to monitor the activity of these units in the awake, head-fixed animal using large standard sized cameras mounted on heavy camera arms. However, we need a capability to conduct such monitoring in the awake and freely moving animal so that we can relate specific patterns of cortical activity to natural behaviors.

Licensing Contact

Taylor Jordan

615.936.7505

Inventors

Jack Noble, Benoit Dawant
Category:
Medical Imaging

System for Determining the Orientation of a Bone-Implanted Anchor

A method for simplifying the process of designing a platform for minimally invasive surgery. The platform is designed to attach to a set of bone-implanted anchors attached to the patient. This method makes the fitting of the platform to the anchors simpler and easier.

Licensing Contact

Taylor Jordan

615.936.7505

Inventors

J Michael Fitzpatrick
Category:
Medical Devices

HEK-293 Cell Line Containing the Human Norepiephrine Transporter cDNA (Norepi Cell Line)

Licensing Contact

Karen Rufus

615.322.4295

Inventors

Randy Blakely
Category:
Research Tools
Field of Use:
Cardiovascular
Research Tool Type:
Cell Line

MMP-7 Null Mice

The only MMP-7-null mouse that has been generated. Used to determine biological function of MMP-7. Mice have been used in more than 10 publications at this point, and will be distributed by a commercial vendor in the near future.

Licensing Contact

Karen Rufus

615.322.4295

Inventors

Lynn Matrisian, Carole Wilson
Category:
Research Tools
Field of Use:
Cardiovascular Inflammatory/Immune Oncology
Research Tool Type:
Animal Model