Inflammatory/Immune

Displaying 1 - 8 of 8


Anti-human Myeloid Cell Nuclear Differentiation Monoclonal Antibody

The antibody is a rat IgG1 monoclonal, clone 3C1.


Licensing Contact

Jody Hankins

615.322.5907
Research Tools
Antibody
Inflammatory/Immune

Anti-Armadillo Repeat Gene Deleted in Velo-cardiofacial Syndrome Monoclonal Antibody

This research targets ARVCF.


Licensing Contact

Karen Rufus

615.322.4295

Inventors

Albert Reynolds
Research Tools
Antibody

Floxed Prostaglandin D2 Receptor Alleles

This research targets DP1.


Licensing Contact

Karen Rufus

615.322.4295

Inventors

Richard Breyer
Research Tools
Animal Model

Carboxylic Acid Amides as Selective COX-2 Inhibitors

A method of treating animals having cancer by administration of secondary amide derivatives of various COOH-containing drugs, such as COOH-containing NSAIDs, for instance, indomethacin.


Licensing Contact

Mike Villalobos

615.322.6751

Novel Esters and Amides Derived from Indolealkanol and Indolealkylamines as Selective Cyclooxygenase-2 (Cox-2) Inhibitors

A compound of the formula ##STR1## where: n, and X are as defined in the specification, and the compound possesses selectivity for inhibition of cyclooxygenase-2.


Licensing Contact

Mike Villalobos

615.322.6751
Therapeutics
Inflammatory/Immune

Lipoxygenase Proteins and Nucleic Acids

Isolated and purified lipoxygenase proteins and nucleic acids are described. Particularly, a novel human 15(S) lipoxygenase (15-Lox-2) protein and cDNA and a cDNA for mouse 8S-lipoxygenase are described. Recombinant host cells, recombinant nucleic acids and recombinant proteins are also described, along with methods of producing each. Isolated and purified antibodies to 15-Lox-2 and 8-Lox, and methods of producing the same, are also described.


Licensing Contact

Janis Elsner

615.343.2430

Inventors

Alan Brash

EP4 Transgenic Mice

EP4 Transgenic Mice are part of the Vanderbilt Research Tools Catalog.


Licensing Contact

Karen Rufus

615.322.4295

MMP-7 Null Mice

The only MMP-7-null mouse that has been generated. Used to determine biological function of MMP-7. Mice have been used in more than 10 publications at this point, and will be distributed by a commercial vendor in the near future.


Licensing Contact

Karen Rufus

615.322.4295