Nucleic Acid/Plasmid

Displaying 1 - 2 of 2

Recombinant Human Sodium Channel Nav1.5 with Long-QT Syndrome (LQT3) Mutations

Mammalian expression plasmids encoding mutant human voltage-gated sodium channel (NaV1.5) cDNA for use in heterologous expression studies. The plasmids encode versions of NaV1.5 with specific mutations identified in patients with congenital long-QT syndrome type 3 (LQT3 mutations).

Licensing Contact

Karen Rufus

615.322.4295

Inventors

Alfred George
Category:
Research Tools
Research Tool Type:
Nucleic Acid/Plasmid

Heterologous Expression System for Studying Recombinant Human Brain Voltage-Gated Sodium Channel, SCN1A

Isolated nucleic acids encoding human SCN1A polypeptides, recombinantly expressed and isolated human SCN1A polypeptides, heterologous expression systems for recombinant expression of human SCN1A polypeptides, assay methods employing the same, and methods and compositions for modulation of sodium channel function.

Licensing Contact

Karen Rufus

615.322.4295

Inventors

Alfred George, Christoph Lossin
Category:
Research Tools
Research Tool Type:
Nucleic Acid/Plasmid