Browse Technologies

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COX2 Probes for Multimodal Imaging

Inventors at Vanderbilt University have developed a novel chemical design and synthesis process for azulene-based COX2 contrast agents which can be used for molecular imaging, via a variety of imaging techniques. These COX2 probes can be utilized for numerous applications, including imaging cancers and inflammation caused by arthritis and cardiovascular diseases. The process for developing these COX2 contrast agents has been significantly improved through a convergent synthesis process which reduces the required steps to establish the COX2 precursors.


Licensing Contact

Masood Machingal

615.343.3548
Medical Imaging

Cuffed Inner Cannula and Flexible Outer Cannula Tracheostomy Tube

This new tracheostomy tube design prevents the need for decannulation when changing from a cuffed to cuffless (or vice versa) tracheostomy. It also enables a comfortable and fit in patients with both large and small neck diameters. The tube enhances patient safety by maintaining the airway at all times when downsizing or upsizing.


Licensing Contact

Taylor Jordan

615.936.7505
Medical Devices

Endonasal Surgical Robot for Sinus and Neurosurgery

Vanderbilt engineers have developed a robotic system for performing sinus and neurosurgery through the nose. This provides a less invasive way to access surgical sites in the sinuses and near the middle of the patient's head, leading to faster recovery times. The robot is modular and sterilizable with detachable cartridge-based instruments. Each instrument is a concentric tube robot, which is a needle-sized tool that can bend and elongate. The system delivers four of these instruments through a single nostril.


Licensing Contact

Ashok Choudhury

615.322.2503

Flexible Instrument with Pre-curved Elements for Surgical Tools

Vanderbilt researchers have developed a novel system for allowing surgical instruments to navigate around tighter corners and access difficult-to-reach areas in the body. This system uses pre-curved elastic elements added on to the existing instrument. Current surgical instruments are manufactured in a straight-line configuration, which means they must bend in order to reach around obstructions in surgery. By adding pre-curved sections, some of the bending is already accomplished, allowing the instrument to bend around tighter corners.


Licensing Contact

Ashok Choudhury

615.322.2503

Guide Wire Torque Device for Interventional Medical Procedures

Vanderbilt University researchers have created a torque device that allows surgeons to apply better torque and grip to guide wires used in interventional medical procedures.


Licensing Contact

Chris Harris

615.343.4433

Inventors

Michael Nichols
Medical Devices

Heterogeneous catalysis of NMR Signal Amplification by Reversible Exchange(SABRE)

Vanderbilt researchers have developed heterogeneous catalysis and catalyst for the NMR Signal Amplification by Reversible Exchange (SABRE) hyperpolarization process. Coupled with the researchers' development of a method to perform SABRE in aqueous solutions, this discovery could allow fully biocompatible SABRE hyperpolarization processes in water with catalyst recycling. This would allow the production of pure aqueous contrast agents requiring only parahydrogen as a consumable.


Licensing Contact

Chris Harris

615.343.4433
Medical Imaging

Low-cost, Normally Closed Microfluidic Valve

Vanderbilt researchers have developed a normally closed valve that is able to provide selective movement of small fluid quantities in a microfluidic device. The present microfluidic valve can be actuated using a simple rotating drivehead and mechanical support, greatly simplifying the valve design.


Licensing Contact

Ashok Choudhury

615.322.2503

Miniature Optical Coherence Tomography Probe for Real-time Monitoring of Surgery

Vanderbilt researchers have designed a forward scanning miniature intraoperative Optical Coherence Tomography (OCT) probe that can be used for diagnostic purposes and real-time monitoring of surgery within small spaces, such as endoscopic surgery, intraocular surgery, and other microsurgery.


Licensing Contact

Taylor Jordan

615.936.7505

Minimally Invasive Telerobotic Platform for Transurethral Exploration and Intervention

This technology, developed in Vanderbilt University's Advanced Robotics and Mechanism Applications Laboratory, uses a minimally invasive telerobotic platform to perform transurethral procedures, such as transurethral resection. This robotic device provides high levels of precision and dexterity that improve patient outcomes in transurethral procedures.


Licensing Contact

Masood Machingal

615.343.3548
Medical Devices
Genitourinary

Model-based Compression Correction Framework for Ultrasound

Vanderbilt researchers have developed a system that corrects for compressional effects in ultrasound data during soft tissue imaging. The system uses tracking and digitization information to detect the pose of the ultrasound probe during imaging, and then couples this information with a biomechanical model of the tissue to correct compressional effects during intraoperative imaging.


Licensing Contact

Philip Swaney

615.322.1067