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There is an urgent need to identify reliable predictors of opioid responses to develop personalized opioid therapy for chronic pain management.

A well-known, four-year study found popular arthritis drug Celebrex no more dangerous for the heart than older drugs in its same classification – commonly called NSAIDs.

A collaboration between Vanderbilt University professors of chemistry and medicine yielded a promising compound to treat arrhythmia from an unlikely place: the fungal natural product verticilide.

The release of neurotransmitters and hormones in the body is tightly controlled by complex protein machinery embedded in cell membranes.

An international team involving Vanderbilt researchers has discovered that a new “checkpoint” protein on immune system cells is active in tumors, and that blocking it — in combination with other treatments — is a successful therapeutic approach in mouse models of cancer.

There have been three U.S. patents issued in February

The epithelial cells that line the intestines build a specialized cell surface — the “brush border” — that processes and absorbs nutrients, and defends against pathogens.

The protein STK17A (serine threonine kinase 17A) appears to play roles in various cancer types.

Researchers at Vanderbilt University Medical Center and colleagues have identified a gene that increases the risk for a severe and potentially life-threatening reaction to the commonly prescribed antibiotic vancomycin.

Novel DNA repair mechanism preserves genome integrity: The new mechanism, which is initiated by a protein called HMCES, was reported in the journal Cell.