Department of Medicine

Displaying 1 - 10 of 31


VISE-affiliated researchers conduct phase 1 trial of novel magnetic endoscope for colonoscopies

A Vanderbilt Institute for Surgery and Engineering (VISE) research team is conducting the first phase 1 clinical trial of a magnetic, flexible endoscope that has the potential to provide a safer alternative to standard colonoscopy, particularly for individuals with inflammatory bowel disease (IBD).

The in-human studies of a magnetically actuated robotic platform for colonoscopy developed by the group, including demonstration of intelligent control with assistive autonomy using magnetic fields, began this month at Vanderbilt University Medical Center.


Study identifies biomarker for breast cancer response to immunotherapy

A biomarker that has proven to be a predictor for response to immunotherapies in melanoma patients also has clinical relevance for breast cancer patients, according to a new study published in Clinical Cancer Research, a journal of the American Association for Cancer Research.


Endotoxin shock protector

Using a novel cell-penetrating peptide they designed and tested in mice that selectively suppresses nuclear transport through importin alpha 5, Jacek Hawiger, MD, PhD, Jozef Zienkiewicz, PhD, Yan Liu, MD, and colleagues showed that endotoxin shock is mediated by proinflammatory SRTFs rather than lipid-regulating SREBPs.


A new regulator of B cell development

The researchers detected IL-33 during early B cell development in humans and found reduced IL-33 expression in B cell chronic lymphocytic leukemia samples compared to healthy controls.