obesity

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Enzyme protects against obesity-related heart disease

Saturated fats found in high-fat diets increase the risk of heart failure. Now Manisha Gupte, PhD, Hind Lal, PhD, and colleagues show that the presence of an enzyme called GSK-3beta in the heart is crucial to protect against obesity-related cardiac dysfunction.


Pharma Pipeline: Compounds, Core Capabilities, Collaboration

Right now, at Vanderbilt University there are dozens of researchers studying small and large molecules and their effects on various diseases, searching for clues that will lead to the next big drug discovery.