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Development of an AI-assisted System for Automatic Clinical Coding in Otolaryngology
This project aims to develop a computer-assisted coding system based on state-of-the-art artificial intelligence (AI) technology to enable automatic clinical coding. This system is designed to use free-text operative notes written by clinicians as the input and generate the Current Procedural…
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Preclinical Development of a Settable Bone Graft for Stabilization of Dental Implants
The team has designed settable, resorbable poly(thioketal urethane)s that stabilize structural bone defects as they oxidatively degrade and are replaced by new bone. The next-generation poly(thioketal thiourethane)s with improved storage stability have enabled the development of the first bone…
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Ready for REED: Transitioning from MVP to Market-Ready Solution
The project aims to develop a proprietary large language model (LLM) fine-tuned for dialogic reading (DR) to support young children's literacy development. The follow-on award will support the development of a custom LLM trained on expert-curated DR prompts, structured book dialogue, and real…
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Accelerating the Development and Commercialization of a Robot Scientist/Self-Driving Biological Laboratory
This project seeks to develop scalable, 1,000-channel CAPCAS microbioreactor systems to accelerate AI/ML-driven advancements in cell-culture control for biologically produced pharmaceuticals and industrial chemicals. The outcome will enable more efficient cell-line identification, media…
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Learning with Optimal Guidance for Autistic Navigators (LOGAN) Virtual Driving Instruction System
SANDI supports neurodiverse individuals, particularly those on the autism spectrum, in achieving driving independence by addressing barriers like anxiety and sensory overload through structured, repetitive learning. This innovative simulator enhances confidence, provides greater accessibility to…
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A Stabilizing Agent That Enhances the Resistance of Probiotics and Recombinant Enzymes to Heat and Desiccation
This technology will use the bacterial hydrophilin DtpA to enhance the stability and viability of probiotics and enzymes under extreme conditions, improving strain diversity, bacterial recovery, and enzyme protection for microbiome-based therapeutics.
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