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Preclinical Testing of Resorbable Surgical Mesh
This proposal aims to develop poly(thioketal thiourethane) (PTKTUR) elastomers for surgical mesh that support tissue regeneration and degrade in response to cell-secreted reactive oxygen species, with tunable mechanical properties matching patient biology.
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Developing a Novel Platform for Social Science Research Using LLM Persona-Agents
The team is developing an automated, text-based platform with customizable persona-agents to simulate social interactions, enabling research on how conversations influence beliefs, disinformation, and radicalization in chat-based environments.
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Intrinsic Glove: Saving Traumatized Hands
The team is developing the Intrinsic Glove, a semi-rigid, flexible orthosis designed to improve hand trauma management by promoting safe positioning, early motion, and compression. This innovative glove enhances patient care and provider efficiency by enabling quick, effective positioning and…
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Waiting Room Stories, Product Development Phase
This initiative aims to transform the hospital waiting room experience by providing patients with a curated playlist of stories, offering comfort and connection during a typically isolating and stressful time. The project will develop a user-friendly digital platform to deliver these stories and…
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TissueAb: An Unbiased in Vivo Screening Platform to Identify Tissue Targeting Antibodies
The team will develop a platform using phage display libraries to identify antibody variants specific to targeted tissues, enhancing the development of biologics for immune-oncology, autoimmunity, and other diseases through in vivo screening and next-generation sequencing.
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Wearable Extracorporeal Membrane Oxygenation System for Safer Patient Ambulation
The team aims to create a portable extracorporeal life support system that integrates a blood pump, oxygenator, and user interface, enabling ambulatory ECMO use to improve patient mobilization and outcomes, particularly for those awaiting lung transplants.
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