NIH

• 
• 
• 
• 

Monocytes are known to play an important role in hypertension, although the exact mechanism remains unclear. It is hypothesized that a potential source of monocyte activation originates from its interaction with the vascular endothelium.

Efforts to explore the landscape of small RNAs (sRNAs) — short RNA molecules that are poorly understood — often use high-throughput sequencing (sRNA-seq). These efforts are hampered by a lack of tools to identify, quantify and analyze all the different sRNAs in sRNA-seq datasets.