Single-cell RNA sequencing is a powerful tool for studying cellular diversity, for example in cancer where varied tumor cell types determine diagnosis, prognosis and response to therapy.
Small cell lung cancer (SCLC) represents up to 25 percent of lung cancer cell deaths and is associated with early metastasis and poor patient survival.
Cancers of the tonsils and the base of the tongue related to the human papillomavirus (HPV) are frequently small, often with no early-stage symptoms, so many patients go undiagnosed until tumors have spread to lymph nodes in the neck.
Computer scientists from around the globe are using a one-stop shop to find research results that could help them move the field of cyber-physical systems forward, improving the relationships between humans, computers and the physical world that can make life safer, energy-efficient and more convenient.
Glaucoma is characterized by degeneration of retinal ganglion cells, leading to irreversible vision loss. Currently, the only treatable glaucoma risk factor is increased intraocular pressure.
Many cells, including cancer cells, are known to secrete short RNAs in tiny vesicles, which then move inside other cells — potentially a form of cell-to-cell communication.
A $10 million gift from alumna Jennifer R. Frist, BS’93, and husband William R. “Billy” Frist will endow a new center focused on supporting and developing the neurodiverse talents of individuals with autism at Vanderbilt University’s School of Engineering.