Browse Technologies

Displaying 41 - 49 of 49


Anti-Armadillo Repeat Gene Deleted in Velo-cardiofacial Syndrome Monoclonal Antibody

This research targets ARVCF.


Licensing Contact

Karen Rufus

615.322.4295

Inventors

Albert Reynolds
Research Tools
Antibody

A Method for Genetically Engineering Proteins with Cell Membrane Translocating Activity

The invention describes a membrane-translocating peptide sequence (MTS) which facilitates entry of polypeptides and proteins into cells. Also described is an isolated nucleotide sequence encoding the membrane-translocating peptide and a method of using this sequence to genetically engineer proteins with cell membrane permeability. The MTS, and the method of genetically engineering proteins with cell membrane permeability, are useful for polypeptide and protein delivery for human and veterinary applications such as vaccine delivery and cancer therapy.


Licensing Contact

Seema Sinha

615.343.2430
Research Tools

Lipoxygenase Proteins and Nucleic Acids

Isolated and purified lipoxygenase proteins and nucleic acids are described. Particularly, a novel human 15(S) lipoxygenase (15-Lox-2) protein and cDNA and a cDNA for mouse 8S-lipoxygenase are described. Recombinant host cells, recombinant nucleic acids and recombinant proteins are also described, along with methods of producing each. Isolated and purified antibodies to 15-Lox-2 and 8-Lox, and methods of producing the same, are also described.


Licensing Contact

Seema Sinha

615.343.2430

Stably-Transfected (HEK-293 cells) Human Serotonin Transporter (hSERT) Cell Line

HEK-293 cells stably-Transfected with Human Serotonin Transporter (hSERT)


Licensing Contact

Karen Rufus

615.322.4295

Inventors

Randy Blakely
Research Tools
Cell Line

Integrated Device for Leaching Extraction and Assessment

The invention is a device which permits the direct quantification of leachable organic constituents from within solid materials. It is expected that the device will be used in landfills and in other environments where measurements are central to the evaluation of the environmental compatibility of solid materials (e.g., sediments, soils, solidified waste forms) containing organic constituents that have the potential to degrade water resources of to be taken up by biota and the food chain. The invention is designed to simplify current difficulties in assessing leaching of organic constituents with low aqueous solubility.


Licensing Contact

Chris Harris

615.343.4433
Research Tools

Heterologous Expression System for Studying Recombinant Human Brain Voltage-Gated Sodium Channel, SCN1A

Isolated nucleic acids encoding human SCN1A polypeptides, recombinantly expressed and isolated human SCN1A polypeptides, heterologous expression systems for recombinant expression of human SCN1A polypeptides, assay methods employing the same, and methods and compositions for modulation of sodium channel function.


Licensing Contact

Karen Rufus

615.322.4295
Research Tools
Nucleic Acid/Plasmid

EP4 Transgenic Mice

EP4 Transgenic Mice are part of the Vanderbilt Research Tools Catalog.


Licensing Contact

Karen Rufus

615.322.4295

HEK-293 Cell Line Containing the Human Norepiephrine Transporter cDNA (Norepi Cell Line)


Licensing Contact

Karen Rufus

615.322.4295

Inventors

Randy Blakely
Research Tools
Cell Line
Cardiovascular

MMP-7 Null Mice

The only MMP-7-null mouse that has been generated. Used to determine biological function of MMP-7. Mice have been used in more than 10 publications at this point, and will be distributed by a commercial vendor in the near future.


Licensing Contact

Karen Rufus

615.322.4295