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HEK Cells with Stable Expression of Human Brain Sodium Channel Nav1.1 Subunits (SCN1A, SCN1B, and SCN2B)

This is a human embryonic kidney cell line that stably expresses the three component proteins of the brain Navl.l voltage-gated sodium channel (SCNlA, SCNlB and SCN2B). The invention is important because mutation of the gene SCNlA is the most common cause of inherited epilepsy syndromes. In addition, voltage- gated sodium channels are important drug targets for anticonvulsant therapies. To our knowledge, this is the first cell line to simultaneously express all three components of Navl.l. The expression of all three proteins has been confirmed using western blot analysis. The stable cell line expresses the appropriate Nav


Licensing Contact

Karen Rufus

615.322.4295
Research Tools
Cell Line
Neuroscience/Neurology

HCC2429 Human Lung Cancer Cell Line

This research targets HCC2429.


Licensing Contact

Karen Rufus

615.322.4295
Research Tools
Cell Line
Oncology

Floxed Prostaglandin D2 Receptor Alleles

This research targets DP1.


Licensing Contact

Karen Rufus

615.322.4295

Inventors

Richard Breyer
Research Tools
Animal Model

Floxed Endoplasmic Reticulum Kinase (Perk) mice

This research targets Perk.


Licensing Contact

Karen Rufus

615.322.4295

Inventors

Douglas Cavener
Research Tools
Animal Model
Oncology

Endothieal Nitric Oxide Synthase Null Mice (db/db background)

This research targets eNOS.


Licensing Contact

Karen Rufus

615.322.4295

Inventors

Raymond Harris
Research Tools
Animal Model
Cardiovascular

Anti-Clostridium Difficile Toxin A (c-terminal) Mouse Monoclonal Antibody

This antibody binds to the delivery domain of Clostridium difficile Toxin A.


Licensing Contact

Jody Hankins

615.322.5907
Research Tools
Antibody
Infectious Disease

Cell Line with Stable Expression of Mutant Human Voltage Gated Sodium Channel 1.1 (R1648H)

This research targets Nav1.1.


Licensing Contact

Karen Rufus

615.322.4295
Research Tools
Cell Line
Neuroscience/Neurology

Cell Line with Stable Expression of Human Brain Sodium Channel Nav1.2, SCN1B, and SCN2B

This research targets Nav1.2.


Licensing Contact

Karen Rufus

615.322.4295
Research Tools
Cell Line
Neuroscience/Neurology

B53 CHO Cell Line with Inducible VDJ Recombinase Expression

This research targets VDJ recombinase.


Licensing Contact

Karen Rufus

615.322.4295

Inventors

Eugene Oltz
Research Tools
Cell Line
Oncology Research Reagent

Anti-p19 ARF Antibody

This research targets ARG(p19).


Licensing Contact

Mike Villalobos

615.322.6751

Inventors

Stephen Hann
Research Tools
Antibody
Oncology