This is a human embryonic kidney cell line that stably expresses the three component proteins of the brain Navl.l voltage-gated sodium channel (SCNlA, SCNlB and SCN2B). The invention is important because mutation of the gene SCNlA is the most common cause of inherited epilepsy syndromes. In addition, voltage- gated sodium channels are important drug targets for anticonvulsant therapies. To our knowledge, this is the first cell line to simultaneously express all three components of Navl.l. The expression of all three proteins has been confirmed using western blot analysis. The stable cell line expresses the appropriate Nav