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Recombinant Human Sodium Channel Nav1.5 with Long-QT Syndrome (LQT3) Mutations

Mammalian expression plasmids encoding mutant human voltage-gated sodium channel (NaV1.5) cDNA for use in heterologous expression studies. The plasmids encode versions of NaV1.5 with specific mutations identified in patients with congenital long-QT syndrome type 3 (LQT3 mutations).


Licensing Contact

Karen Rufus

615.322.4295

Inventors

Alfred George
Research Tools
Nucleic Acid/Plasmid

Metabolic Labeling Reagents for Chondroitin Sulfate

Dr. Patrick Page-McCaw has developed synthetic analogs of N-acetylgalactosamine, finally enabling researchers to track the biosynthesis of chondroitin sulfate along with other glycans. These stunning images demonstrate incorporation of these metabolic labeling reagents to track neurodevelopmental processes in a zebrafish model system. Notably, the metabolic label can be detected post vivo using a standard ""click"" chemistry reaction. Further, Dr. Page-McCaw has optimized a background reduction strategy to complement this technology by improving the signal-to-noise ratio.


Licensing Contact

Mike Villalobos

615.322.6751
Research Tools
Imaging
Research Reagent

Tissue Specific Expression of Serotonin Transporter in Transgenic Mouse

This research targets SERT.


Licensing Contact

Karen Rufus

615.322.4295

Rabbit Anti-Fibroblast Specific Protein 1 Polyclonal Antibody

This research targets FSP1.


Licensing Contact

Karen Rufus

615.322.4295

Inventors

Eric Neilson
Research Tools
Antibody

Prostaglandin E Receptor-2 Null Mice

Prostaglandin E receptor-2 (EP2) null mice on a C57BL/6 background.


Licensing Contact

Karen Rufus

615.322.4295
Research Tools
Animal Model
Cardiovascular

Primary Human Fibroblats Derived From Prostate Cancer Tissue and Normal Tissue

This research targets prostate cancer.


Licensing Contact

Karen Rufus

615.322.4295
Research Tools
Cell Line
Oncology

Pancreas Transcription Factor-1 Alpha-Cre Transgenic Mice

This research targets Ptf1a.


Licensing Contact

Karen Rufus

615.322.4295

Inventors

Christopher Wright
Research Tools
Animal Model
Oncology

Pancreas Specific Trangenic Mice Overexpressing Either Transmembrane Heparin-binding EGF-like Growth Factor or Secreted HB-EGF

This research targets HB-EGF.


Licensing Contact

Karen Rufus

615.322.4295

Inventors

Anna Means
Research Tools
Animal Model

Mouse Model for Cardiovascular/Autonomic Disorders

This research targets CHT.


Licensing Contact

Karen Rufus

615.322.4295
Research Tools
Animal Model

Mouse Anti-Kaiso Monoclonal Antibody

This research targets Kaiso.


Licensing Contact

Karen Rufus

615.322.4295

Inventors

Albert Reynolds
Research Tools
Antibody
Oncology