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Scn1a Knockout Mouse Genetic Model of Epilepsy

This is a unique genetically modified strain ofmice that models Dravet syndrome, a severe infant-onset epileptic encephalopathy. They are maintained on apure 129S6/SvEvTac genetic background to facilitate genetic studies.


Licensing Contact

Karen Rufus

615.322.4295
Research Tools
Animal Model

Immortalized Mouse Epididymal Epithelial Cell Lines

These cell lines are useful for studying the regulation of tissue-specific gene expression, and may also be used to identify epididymal-specific transcription factors involved in expression of specific proteins in the epididymis.


Licensing Contact

Cameron Sargent

615.343.2430
Research Tools
Genitourinary
Cell Line

GluN2B Floxed Mice (also called NR2B, glutamate receptor 2B)

Allows for targeted deletion of the GluN2B subunit of NMDA receptors in specific cells or at specific times during development, juvenile, or adult stages. C57BL6/J background


Licensing Contact

Cameron Sargent

615.343.2430

Inventors

Eric Delpire
Research Tools
Neuroscience/Neurology
Animal Model

Endothieal Nitric Oxide Synthase Null Mice (db/db background)

This research targets eNOS.


Licensing Contact

Karen Rufus

615.322.4295

Inventors

Raymond Harris
Research Tools
Cardiovascular
Animal Model

Rabbit-Anti-mouse Pancreatic and Duodenal Homebox Gene-1 Antibody

This research targets Pdx-1.


Licensing Contact

Cameron Sargent

615.343.2430

Inventors

Christopher Wright

Cleavable Surfactants for the Analysis of Proteins and Other Biological and Chemical Samples


Licensing Contact

Karen Rufus

615.322.4295
Research Tools
Mass Spectrometry Tools

Screening Assay for Molecules That Alter Cell Cycle Rhythm

This research targets Cell Cycle.


Licensing Contact

Karen Rufus

615.322.4295
Research Tools
Oncology
Assays/Screening

Mice with Inducible Cre-ERt Replacing Cytokeratin 19 Coding Region

This research targets CK19.


Licensing Contact

Taylor Jordan

615.936.7505

Inventors

Guoqiang Gu, Anna Means
Research Tools
Oncology
Animal Model

Slc5a7 (choline transporter, CHT) BAC Transgenic Mouse

A Bacterial Artificial Chromosome (BAC) containing the mouseSlc5a7 gene was used to make transgenic mice. Mice show elevated choline transporter and acetylcholine levels and increased treadmill endurance.


Licensing Contact

Karen Rufus

615.322.4295

Inventors

Randy Blakely
Research Tools
Animal Model

Recombinant Human Sodium Channel Nav1.5 with Long-QT Syndrome (LQT3) Mutations

Mammalian expression plasmids encoding mutant human voltage-gated sodium channel (NaV1.5) cDNA for use in heterologous expression studies. The plasmids encode versions of NaV1.5 with specific mutations identified in patients with congenital long-QT syndrome type 3 (LQT3 mutations).


Licensing Contact

Karen Rufus

615.322.4295

Inventors

Alfred George
Research Tools
Nucleic Acid/Plasmid