Browse Technologies

Displaying 41 - 45 of 45


PANORAMIC: Precession and Nutation for Observing Rotation at Multiple Intervals about the Carrier

Methods of hyperpolarization based on parahydrogen have been expanding recently from the early applications in hydrogenation chemistry to biomedical imaging where they are expected to yield similar information as the competing technology, dynamic nuclear polarization, (DNP). These hyperpolarization experiments have already enabled the measurement of metabolism in vivo at temporal resolutions of seconds. When infused into organisms harboring tumor cells, molecules such as pyruvate and lactate have been shown to be sufficiently long-lived to infiltrate cellular metabolic cycles and be converted at different rates in cancer versus normal tissue. DNP has been used most frequently in these early studies, owing to commercial availability and the flexibility to polarize small molecules such as pyruvate and lactate. Techniques based on chemical addition or exchange of parahydrogen have also shown promise for generating metabolic contrast in vivo at similar levels of signal enhancement and at lower costs.


Licensing Contact

Chris Harris

615.343.4433

Inventors

Kevin Waddell
Medical Imaging

Image-Guided Navigation System for Endoscopic Eye Surgery

A flexible endoscope for ophthalmic orbital surgery is presented. The endoscope has illuminating fiber, image fiber and a free conduit to deliver purge gas/fluid in addition to instruments such as ablation instruments, coagulating instrument or a medication delivery instrument.


Licensing Contact

Philip Swaney

615.322.1067

Combined Raman Spectroscopy- Optical Coherence Tomography (RS-OCT)

Vanderbilt researchers have developed an optical system for the differentiation of normal and cancerous skin lesions. The system combines the diagnostic prowess of two separate techniques to provide non-invasive, real-time, in-situ evaluation of lesions.


Licensing Contact

Ashok Choudhury

615.322.2503

Trimodal Handheld Probe Based on Raman Spectroscopy and Confocal Imaging for Cancer Detection

This technology relates to a device and method for non-invasive evaluation of a target of interest of a living subject, and in particular to devices and methods that integrate confocal imaging with confocal Raman spectroscopy, for non-invasive evaluation of the biochemical compositions and morphological details of normal and cancerous skin lesions of a living subject.


Licensing Contact

Ashok Choudhury

615.322.2503

Method for the Automatic Segmentation of the Facial Nerve and the Chorda Tympani in CT Images

This is a high resolution imaging device that can detect the fundamental functional units of cortical organization. Currently, with existing technology, we are able to monitor the activity of these units in the awake, head-fixed animal using large standard sized cameras mounted on heavy camera arms. However, we need a capability to conduct such monitoring in the awake and freely moving animal so that we can relate specific patterns of cortical activity to natural behaviors.


Licensing Contact

Taylor Jordan

615.936.7505
Medical Imaging