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Systems-Biology Infrastructure to Identify Drug Repurposing Opportunities as Antiviral & Anticancer Therapeutics

Vanderbilt researchers have developed an in-silico screening method to reveal new indications for existing drugs with known protein targets using a novel infrastructure. The infrastructure integrates multiple factors across system-biology models to create a drug discovery pipeline.

Licensing Contact

Clarissa Muere

615.343.2430

Inventors

Don Rubin, Feixiong Cheng, Zhongming Zhao
Category:
Bioinformatics Therapeutics

Marker Enrichment Modeling (MEM) Software for Automated Cell Population Characterization and Identification in Complex Tissue Microenvironments

Marker enrichment modeling (MEM) provides a crucial missing piece for true machine learning analysis of cell identities and phenotypes in complex tissue microenvironments, including human immune disorders and cancer.

Licensing Contact

Masood Machingal

615.343.3548

Inventors

Jonathan Irish, Kirsten Diggins
Category:
Bioinformatics Computer Science & Communications Medical Imaging Research Tools

TagDock: An Efficient Rigid Body Molecular Docking Algorithm For Three Dimensional Models of Oligomeric Biomolecular Complexes With Limited Experimental Restraint Data

TagDock is an efficient rigid body molecular docking algorithm that generates three-dimensional models of oligomeric biomolecular complexes in instances where there is limited experimental restraint data to guide the docking calculations. Through "distance difference analysis" TagDock additionally recommends followup experiments to further discriminate divergent (score-degenerate) clusters of TagDock's initial solution models

Licensing Contact

Masood Machingal

615.343.3548

Inventors

Terry Lybrand, Jarrod Smith, Christopher Moth, Sarah Edwards
Category:
Bioinformatics Computer Science & Communications Research Tools

KnowledgeMap: Comprehensive Curriculum Content Management and Mapping System for Medical Education

KnowledgeMap is a web accessible comprehensive content management system with robust mapping capabilities across the entire curriculum (at the level of full lectures, not just outlines or syllabi) that facilitates overall design, management, and evaluation of a coherent and coordinated curriculum.

Licensing Contact

Taylor Jordan

615.936.7505

Inventors

Anderson Spickard, Joshua Denny, Randolph Miller, Jeffrey Smithers, Glenn Stein
Category:
Bioinformatics Computer Science & Communications Health Care IT