Browse Technologies

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Adaptive PCR: A PCR control system to overcome challenging conditions

A PCR control system to overcome challenging conditions. By directly monitoring the hybridization of fluorescently labelled L-DNA mimics of the template DNA strands and primers, it is possible to improve the efficiency of PCR in challenging conditions. This approach eliminates some of the sample preparation and trial and error that would otherwise be required for difficult sample types such as urine or other samples that contain high levels of salts.  In addition, this approach enables on-demand PCR in most any environment.


Licensing Contact

Jody Hankins

615.322.5907
Research Reagent

Non-Invasive Bacterial Identification for Acute Otitis Media using Raman Spectroscopy

Real-time non-invasive Raman Sprectoscopy system to detect the presence and identity of pathogens involved in causing middle ear infections.


Licensing Contact

Ashok Choudhury

615.322.2503

Non-Invasive Skin Cancer Detection using Raman Spectroscopy-OCT System (Portfolio)

Vanderbilt University researchers have designed a system for non-invasive discrimination between normal and cancerous skin lesions. The system combines the depth-resolving capabilities of OCT technique with Raman Spectroscopy's specificity of molecular chemistry. By linking both imagining techniques into a single detector arm, the complexity, cost, and size of previously reported RS-OCT instruments have been significantly improved. The combined instrument is capable of acquiring data sets that allow for more thorough assessment of a sample than existing optical techniques.


Licensing Contact

Ashok Choudhury

615.322.2503

Systems and Methods for Optical Stimulation of Neural Tissues (Portfolio)

Vanderbilt researchers have developed a novel technique for contactless simulation of the central nervous system.  This involves the use of infrared neural stimulation (INS) to evoke the observable action potentials from neurons of the central nervous system.  While infrared neural stimulation of the peripheral nervous system was accomplished almost a decade ago, this is the first technique for infrared stimulation of the central nervous system. This technology has been protected by a portfolio of issued patents.


Licensing Contact

Ashok Choudhury

615.322.2503

MAESTRO: Non-Robotic Dexterous Laproscopic Instrument with a Wrist providing seven degrees of freedom

Inventors at Vanderbilt University have developed a non-robotic dexterous laparoscopic manipulator with a wrist providing seven-degrees-of-freedom. It provides an interface which intuitively maps motion of the surgeon's hands to the tool's ""hands"". The novel user interface approach provides a natural mapping of motion from the surgeon's hands to the instrument tips.


Licensing Contact

Ashok Choudhury

615.322.2503
Medical Devices

Steerable Needles: A Better Turning Radius with Less Tissue Damage

A team of Vanderbilt engineers and surgeons have developed a new steerable needle that can make needle based biopsy and therapy delivery more accurate. A novel flexure-based tip design provides enhanced steerability while simultaneously minimizing tissue damage. The present device is useful for almost any needle-based procedure including biopsy, thermal ablation, brachytherapy, and drug delivery.


Licensing Contact

Ashok Choudhury

615.322.2503

A Device and Method for Vascular or Nerve Separation and Bridging

Vanderbilt researchers have designed a device and method for separating an arteriole that passes over a vein and restricts the passage of blood flow in the eye, which if uncorrected can lead to hemorrhage and vision loss. The device surgically separates the two vessels and then places a stent or bridge between them to alleviate compression. Visualization during the procedure is provided with optical coherence tomography (OCT), and the surgical tool can be either hand-held or robotic.


Licensing Contact

Ashok Choudhury

615.322.2503
Medical Devices

A Novel Organs-On-Chip Platform

Vanderbilt researchers have created a new multi-organs-on-chip platform that comprises Perfusion Control systems, MicroFormulators, and MicroClinical Analyzers connected via fluidic networks. The real-time combination of multiple different solutions to create customized perfusion media and the analysis of the effluents from each well are both controlled by the intelligent use of a computer-operated system of pumps and valves. This permits, for the first time, a compact, low-cost system for creating a time-dependent drug dosage profile in a tissue system inside each well.


Licensing Contact

Ashok Choudhury

615.322.2503

A Robotic System for Treating Intracranial Hemorrhage (ICH)

Vanderbilt researchers have designed a general purpose system for precise steering of multi-lumen needles. One significant application of the system is decompression of the cranium during hemorrhagic events (ICH).


Licensing Contact

Ashok Choudhury

615.322.2503

An Imaging Approach to Detect Parathyroid Gland Health During Endocrine Surgery

Vanderbilt researchers have designed a laser speckle imaging device to detect parathyroid gland viability during endocrine surgery, during which otherwise healthy parathyroid glands are prone to devascularization leading to long-term hypocalcemia. Currently, the surgeon must use his or her best judgement regarding the health of the parathyroid gland. This technology removes the guess work from the decision and provides a real-time assessment of the parathyroid viability.


Licensing Contact

Ashok Choudhury

615.322.2503
Medical Devices