Browse Technologies

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mGlu3 NAMs as Therapeutics for Chemoresistant Tumors

Targeting metabotropic glutamate receptor 3 (mGlu3) has been linked as a potential therapeutic to many neurological disorders and well as oncology through the use of dual specific mGlu2/3 Antagonists (LY341495, RO4491533, MGS0039, RO4988546).


Licensing Contact

Tom Utley

615.343.3852
Therapeutics

TagDock: An Efficient Rigid Body Molecular Docking Algorithm For Three Dimensional Models of Oligomeric Biomolecular Complexes With Limited Experimental Restraint Data

TagDock is an efficient rigid body molecular docking algorithm that generates three-dimensional models of oligomeric biomolecular complexes in instances where there is limited experimental restraint data to guide the docking calculations. Through "distance difference analysis" TagDock additionally recommends followup experiments to further discriminate divergent (score-degenerate) clusters of TagDock's initial solution models


Licensing Contact

Masood Machingal

615.343.3548

Biophotonic Pancreatic Cancer Margin Detection

Vanderbilt researchers have developed an autofluorescence-based system for intraoperative margin assessment of pancreatic cancers. Also under development is the application of the same underlying technology to optimize pancreatic islet cell visualization and extraction to improve the efficiency of islet cell transplantation.


Licensing Contact

Ashok Choudhury

615.322.2503
Medical Devices

Automated clinical documentation software for emergency medical environments

Vanderbilt researchers have developed a system to automatically detect different clinical procedures in order to prevent information loss through patient transfers in emergency situations.


Licensing Contact

Masood Machingal

615.343.3548

Nanoporous Atomically Thin Graphene Membranes for Desalination & Nanofiltration

Vanderbilt researchers have developed an atomically thin membrane with extremely high selectivity and permeability for use in desalination and nanofiltration applications.


Licensing Contact

Philip Swaney

615.322.1067

Nanoporous Atomically Thin Breathable Personal Protective Membranes

Vanderbilt researchers have developed an atomically thin membrane with extremely high selectivity and permeability for use in personal protective equipment.


Licensing Contact

Philip Swaney

615.322.1067

A Compact, Lightweight Solution to Portable ECMO

Vanderbilt researchers have developed a novel, extremely compact and lightweight device toprovide extracorporeal life support (ECLS) and membrane oxygenation (ECMO) in austere and militaryenvironments. Miniaturized in-line components allow for minimized materials and improved ease ofapplication in acute medical emergencies, especially in resource deprived conditions.


Licensing Contact

Philip Swaney

615.322.1067
Medical Devices

Ultrasound Device for Underwater High Resolution Imaging in Turbid Water

A team of Vanderbilt researchers has developed a novel system for producing 3D, real-time, high-resolution visualization within arms reach of a diver. The system uses a custom ultrasound array and mirror system in conjunction with software and algorithms to overcome the limitations of existing systems, enabling the diver to see through turbid water in real-time.


Licensing Contact

Philip Swaney

615.322.1067

Thermoresponsive Printer Filament for Tissue Engineering

Vanderbilt researchers have developed a thermoresponsive filament material for use in 3D printing that can be readily dissolved via cooling. This material has use in a multitude of different applications. One potential application is lost-wax casting for tissue engineering. The present material enables the user to print an intricate vascular structure, embed the structure in an engineered tissue construct, and then dissolve the printed structure to create a hollow vascular network embedded within the tissue construct.


Licensing Contact

Philip Swaney

615.322.1067

System for Transporting, Sorting, and Assembling Nanoscale Objects

Vanderbilt researchers have developed a new system for transporting and sorting nanoscale and mesoscale particles and biomolecules. The system is able to achieve size-based sorting and captures/arranges the particles within a few seconds, which is significantly faster than the existing method of diffusion-based transport.


Licensing Contact

Philip Swaney

615.322.1067

Inventors

Justus Ndukaife