Browse Technologies

Displaying 51 - 60 of 267


NMR Signal Amplification by Reversible Exchange (SABRE) in Water

Vanderbilt researchers have developed a method to perform the Parahydrogen Induced Polarization (PHIP) based method of Signal Amplification by Reversible Exchange (SABRE) in aqueous media. This allows the resulting hyperpolarized molecules to be used for in vivo applications.


Licensing Contact

Chris Harris

615.343.4433
Medical Imaging

Novel anti-platelet therapy for treatment of thrombosis, cardiovascular disease, and cerebrovascular injury

One of the leading causes of deaths in developed countries is related to thromboembolism. PAR-4 (protease activated receptor-4) is one of two receptors on the human platelet that respond to thrombin, the central enzyme of coagulation.  Researchers here at Vanderbilt University have developed novel antagonists of PAR-4 that could be beneficial for patients allowing for normal hemostasis during treatment for thrombotic events.


Licensing Contact

Tom Utley

615.343.3852
Therapeutics
Cardiovascular

Novel Target Regulating Angiogenesis

Vanderbilt scientists have discovered that the receptor tyrosine phosphatase DEP-1 plays a significant role in angiogenesis and that modulation of the DEP-1 receptor with certain agents can affect endothelial cell growth. The research team has developed antibodies that bind to the ectodomain of a mammalian transmembrane protein known as DEP-1 (for density enhanced protein) or CD148. CD148 (also named DEP-1/PTPn) is a receptor-like protein tyrosine phosphatase that is abundantly expressed in vascular endothelial cells, hematopoietic-cell lineages, duct epithelia of thyroid, mammary and gastrointestinal tissues.


Licensing Contact

Mike Villalobos

615.322.6751
Therapeutics

On Chip Polarimetry for HTS

Using microfluidic technology developed by the Bornhop Lab at Vanderbilt, this invention enables the rapid determination of the optical activity of compounds and solutions. Due to the nature of this invention, it is possible to screen a multitude of samples in a high throughput manner in less time with less material and greater accuracy than the industry standards.


Licensing Contact

Janis Elsner

615.343.2430
Research Tools

Organ-on-a-Chip System

Vanderbilt researchers have developed a group of microfluidic organ-on-chip devices that include perfusion controllers, microclinical analyzers, microformulators, and integrated microfluidic measurement chips. Together, these devices can measure and control multiple organ-on-chip systems in order to model the multi-organ physiology of humans.


Licensing Contact

Ashok Choudhury

615.322.2503
Microfluidics

Point of Care Rheological Assay for Sickle Cell Disease

Vanderbilt researchers have created a novel technology for the diagnosis and monitoring of disease states using the rheological properties of a blood sample with a lateral flow membrane.


Licensing Contact

Ashok Choudhury

615.322.2503

Polar Liquid Crystals with High Dielectric Anisotropy

Vanderbilt inventors have developed a new class of liquid crystals with high dielectric anisotropy. A new class of liquid crystals containing boron in their structure has been developed with high dielectric anisotropy, which results in low threshold voltages.


Licensing Contact

Philip Swaney

615.322.1067

Portfolio of Continuum Robotic Systems, Algorithms, and Software Technologies from the Robotics Lab of Professor Nabil Simaan

Professor Simaan and his lab have years of experiencing working collaboratively with commercial entities of various sizes. His research is focused on advanced robotics, mechanism design, control, and telemanipulation for medical applications. His projects have led the way in advancing several robotics technologies for medical applications including high dexterity, snake-like robots for surgery, steerable electrode arrays for cochlear implant surgery, robotics for single port access surgery, and natural orifice surgery.


Licensing Contact

Masood Machingal

615.343.3548
Medical Devices
Genitourinary

Portfolio of Image-Guidance and Organ Localization Technologies from the Lab of Professor Michael Miga

The focus of Dr. Miga's laboratory is on the development of new paradigms in detection, diagnosis, characterization, and treatment of disease through the integration of computational models into research and clinical practice.


Licensing Contact

Philip Swaney

615.322.1067

PosiSeat(TM): Assured Seating of Threaded Surgical Components

Vanderbilt presents an intraoperative device for taking the guesswork out of whether or not a threaded component is securely affixed to bone. This device is an anchor driver that automatically releases upon proper seating of the anchor on the bone of interest.


Licensing Contact

Taylor Jordan

615.936.7505