Browse Technologies

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Latent Image-Derived Features for Prognostic Modeling

Researchers at Vanderbilt have developed a system to estimate prognostic metrics such as the length of a hospital stay, recovery status at discharge, and overall health at discharge, using only baseline imaging and clinical information gathered early in the hospital admission process. This system can assist with medical group operations and planning, it can help to educate families and patients regarding prognosis, and can be used to automatically stage patients for clinical trials.


Licensing Contact

Chris Harris

615.343.4433
Medical Imaging

Local Magnetic Actuation for Obese And Pediatric Patients

Researchers in Vanderbilt University's STORM Lab have developed a novel actuation system that uses magnetic coupling to transmit mechanical power across a physical barrier. This technology is particularly suited for use in minimally invasive surgical procedures for manipulating surgical instruments across tissue barriers.


Licensing Contact

Masood Machingal

615.343.3548
Robotics
Gastrointestinal

Nanostructured Molybdenum (IV) Disulfide (MoS2) Electrodes for use in Solar Cells

Quantum dot sensitized solar cells (QDSSCs) are a widely studied system for harvesting light and converting it to electrical energy. Quantum dots (QDs) are an attractive photoabsorber because they have large absorption coefficients and their energy of absorption in the visible region can be tuned based on their size. Molybdenum (IV) disulfide (MoS2) is a naturally occurring semiconductor found in nature as the mineral molybdenite that can be synthesized from inexpensive, earth-abundant materials for use in solar cells.


Licensing Contact

Chris Harris

615.343.4433

Non-Invasive Bacterial Identification for Acute Otitis Media using Raman Spectroscopy

Vanderbilt researchers have developed an optical-based method for real-time characterization of middle ear fluid in order to diagnose acute otitis media, also knows as a middle ear infection. The present technique allows for quick detection and identification of bacteria and can also be applied to other biological fluids in vivo.


Licensing Contact

Ashok Choudhury

615.322.2503

Non-Invasive Cell Size Detection

Vanderbilt researchers have developed a new method for using contrast enhanced MRI to non-invasively map and quantify cell size on a voxel-by-voxel basis. Using this approach, it is possible to monitor and detect diseases or treatments that alter the distribution of cell sizes such as cancer, muscular dystrophy, hepatocellular hypertrophy, and hypertrophic cardiomyopathy.


Licensing Contact

Chris Harris

615.343.4433
Medical Imaging

Parahydrogen-Induced Polarizer (PHIP)

The present invention provides a PANACEA (Pneumatics Allow Nonmagnetic Actuation for Creation of Enhanced Alignment) polarizer system. This is an integrated assembly of pneumatically actuated, nonmagnetic hydraulic circuits that enable PASADENA chemicals to be efficiently stored, mixed, and reacted in close proximity or within NMR magnetic fields.


Licensing Contact

Chris Harris

615.343.4433

Inventors

Kevin Waddell
Medical Imaging

Porous Materials with Active Sites Created via In-Pore Synthesis

Vanderbilt researchers have synthesized porous adsorbent materials for the capture of toxic industrial chemicals. These adsorbent materials have finely dispersed reactive sites that allow for higher adsorption capacities than existing materials. They can be used in filters for the military, homeland security, first responders, and for a wide range of industrial and commercial catalysts to capture toxic gases such as ammonia and sulfur dioxide.


Licensing Contact

Philip Swaney

615.322.1067

Real-time Detection of Position and Orientation of Wireless Endoscopy Capsule using Magnetic coupling

Vanderbilt researchers have developed a new system to detect the position, orientation, and pressure exerted on surrounding tissues of a wireless capsule endoscopy device.  Magnetic coupling is one of the few physical phenomena capable of transmitting actuation forces across a physical barrier.  Magnetic manipulation has the potential to make surgery less invasive, by allowing untethered miniature devices to enter the body through natural orifices or tiny incisions, and then maneuver with minimal disruption to healthy tissue.  In order to accomplish this goal, the pose (position and orientation) of the medical device must be available in real time.


Licensing Contact

Masood Machingal

615.343.3548

Selective Size Imaging using Filters via Diffusion Times (SSIFT)

Vanderbilt researchers have developed a novel MRI-based method for fast, robust, and accurate imaging of biological tissue by selecting a specific cell size range (such as tumors) without the need for a contrast agent. One exciting application of this method is imaging brain metastases (BM) that are difficult to differentiate from other brain abnormalities such as radionecrosis when using existing approaches.


Licensing Contact

Chris Harris

615.343.4433

Inventors

Junzhong Xu
Medical Imaging

Small Molecule-GIRK Potassium Channel Modulators That Are Anxiolytic Therapeutics

The G-protein activated, inward-rectifying potassium (K+) channels, "GIRKs", are a family of ion channels that has been the focus of intense research interest for nearly two decades. GIRK has been shown to play important roles in the pathophysiology of diseases such as anxiety, epilepsy, Down's syndrome, pain perception and drug addiction. Here scientists at Vanderbilt developed the first truly potent, effective, and selective GIRK activator, ML297 (VU0456810) and demonstrated that ML297 is active in animal models of epilepsy. While the group is using ML297 to continue to explore the therapeutic benefits of GIRK modulation, they are continuing to develop more selective and druggable GIRK inhibitors from different scaffolds.


Licensing Contact

Tom Utley

615.343.3852
Therapeutics
Analgesic