A Method for Genetically Engineering Proteins with Cell Membrane Translocating Activity

Summary

The invention describes a membrane-translocating peptide sequence (MTS) which facilitates entry of polypeptides and proteins into cells. Also described is an isolated nucleotide sequence encoding the membrane-translocating peptide and a method of using this sequence to genetically engineer proteins with cell membrane permeability. The MTS, and the method of genetically engineering proteins with cell membrane permeability, are useful for polypeptide and protein delivery for human and veterinary applications such as vaccine delivery and cancer therapy.

Website

U.S. Patent 6,780,843: Sequence and method for genetic engineering of proteins with cell membrane translocating activity.


Licensing Contact

Janis Elsner

615.343.2430
Tech ID:
VU9841
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