Browse Technologies

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Adaptive PCR: A PCR control system to overcome challenging conditions

Licensing Contact

Jody Hankins

615.322.5907
Research Reagent

A PCR control system to overcome challenging conditions. By directly monitoring the hybridization of fluorescently labelled L-DNA mimics of the template DNA strands and primers, it is possible to improve the efficiency of PCR in challenging conditions. This approach eliminates some of the sample preparation and trial and error that would otherwise be required for difficult sample types such as urine or other samples that contain high levels of salts.  In addition, this approach enables on-demand PCR in most any environment.

Steerable Needles: A Better Turning Radius with Less Tissue Damage

Licensing Contact

Ashok Choudhury

615.322.2503

A team of Vanderbilt engineers and surgeons have developed a new steerable needle that can make needle based biopsy and therapy delivery more accurate. A novel flexure-based tip design provides enhanced steerability while simultaneously minimizing tissue damage. The present device is useful for almost any needle-based procedure including biopsy, thermal ablation, brachytherapy, and drug delivery.

Non-Invasive Bacterial Identification for Acute Otitis Media using Raman Spectroscopy

Licensing Contact

Ashok Choudhury

615.322.2503

Real-time non-invasive Raman Sprectoscopy system to detect the presence and identity of pathogens involved in causing middle ear infections.

Non-Invasive Skin Cancer Detection using Raman Spectroscopy-OCT System (Portfolio)

Licensing Contact

Ashok Choudhury

615.322.2503

Vanderbilt University researchers have designed a system for non-invasive discrimination between normal and cancerous skin lesions. The system combines the depth-resolving capabilities of OCT technique with Raman Spectroscopy's specificity of molecular chemistry. By linking both imagining techniques into a single detector arm, the complexity, cost, and size of previously reported RS-OCT instruments have been significantly improved. The combined instrument is capable of acquiring data sets that allow for more thorough assessment of a sample than existing optical techniques.

Systems and Methods for Optical Stimulation of Neural Tissues (Portfolio)

Licensing Contact

Ashok Choudhury

615.322.2503

Vanderbilt researchers have developed a novel technique for contactless simulation of the central nervous system.  This involves the use of infrared neural stimulation (INS) to evoke the observable action potentials from neurons of the central nervous system.  While infrared neural stimulation of the peripheral nervous system was accomplished almost a decade ago, this is the first technique for infrared stimulation of the central nervous system. This technology has been protected by a portfolio of issued patents.

MAESTRO: Non-Robotic Dexterous Laproscopic Instrument with a Wrist providing seven degrees of freedom

Licensing Contact

Ashok Choudhury

615.322.2503
Medical Devices

Inventors at Vanderbilt University have developed a non-robotic dexterous laparoscopic manipulator with a wrist providing seven-degrees-of-freedom. It provides an interface which intuitively maps motion of the surgeon's hands to the tool's ""hands"". The novel user interface approach provides a natural mapping of motion from the surgeon's hands to the instrument tips.

MultiUse Multimodal Imaging Chelates

Licensing Contact

Taylor Jordan

615.936.7505
Medical Imaging

PK11195 is a high-affinity ligand of the peripheral benzodiazepine receptor (PBR). By linking lanthanide chelates to the PK11195 targeting moiety, Vanderbilt researchers have generated a range of PBR-targeted imaging probes capable of visualizing a number of disease states at cellular levels using a variety of imaging modalities (fl uorescence, PET and SPECT, MRI, electron microscopy).

Load-Bearing Energy Storage Composites from Porous Materials and Methods for Production Thereof

Licensing Contact

Ashok Choudhury

615.322.2503
Energy

A team of Vanderbilt engineers has developed a multifunctional, loadbearing solid-state supercapacitor to simultaneously store energy and withstand static and dynamic mechanical stresses.

IntelliCane: Instrumented cane for diagnosis and evaluation of gait behavior in individuals with mobility issues.

Licensing Contact

Ashok Choudhury

615.322.2503
Medical Devices

This device is designed to assist physical therapists in collection of objective data during gait analysis, to facilitate appropriate assistive gait device prescription, to provide patients and therapists feedback during gait training, and to reduce wrist and shoulder injuries with cane usage.Currently gait characteristics are "measured" in a clinic-based atmosphere. This has two limitations: (i) subjective allocation of "measures" of gait characteristics and (ii) limited data based on trials in the clinic ONLY. What this technology is designed to do is achieve freedom from both of these limitations. The measurements are objective and numerical values (force etc.) and the clinic could provide the cane to the user for obtaining a much more extensive data set including use during normal life activities at home etc.

A Novel Organs-On-Chip Platform

Licensing Contact

Ashok Choudhury

615.322.2503

Vanderbilt researchers have created a new multi-organs-on-chip platform that comprises Perfusion Control systems, MicroFormulators, and MicroClinical Analyzers connected via fluidic networks. The real-time combination of multiple different solutions to create customized perfusion media and the analysis of the effluents from each well are both controlled by the intelligent use of a computer-operated system of pumps and valves. This permits, for the first time, a compact, low-cost system for creating a time-dependent drug dosage profile in a tissue system inside each well.