The only MMP-7-null mouse that has been generated. Used to determine biological function of MMP-7. Mice have been used in more than 10 publications at this point, and will be distributed by a commercial vendor in the near future.
Vanderbilt researchers have designed a cell line with stable expression of the human heart potassium channel, HERG. This cell line has robust and very consistent cell-to-cell HERG activity without detectable endogenous ionic currents, making it ideal to use in preclinical drug screening.