Browse Technologies

Displaying 1 - 10 of 235


Adaptive PCR: A PCR control system to overcome challenging conditions

A PCR control system to overcome challenging conditions. By directly monitoring the hybridization of fluorescently labelled L-DNA mimics of the template DNA strands and primers, it is possible to improve the efficiency of PCR in challenging conditions. This approach eliminates some of the sample preparation and trial and error that would otherwise be required for difficult sample types such as urine or other samples that contain high levels of salts.  In addition, this approach enables on-demand PCR in most any environment.


Licensing Contact

Jody Hankins

615.322.5907
Research Reagent

Steerable Needles: A Better Turning Radius with Less Tissue Damage

A team of Vanderbilt engineers and surgeons have developed a new steerable needle that can make needle based biopsy and therapy delivery more accurate. A novel flexure-based tip design provides enhanced steerability while simultaneously minimizing tissue damage. The present device is useful for almost any needle-based procedure including biopsy, thermal ablation, brachytherapy, and drug delivery.


Licensing Contact

Ashok Choudhury

615.322.2503

Fused in Sarcoma (FUS) Nuclear Translocation Inhibitors for Preventing Fibrosis

The research team has found that one of the key regulators of collagen production in fibrotic diseases is the FUS ribonucleoprotein. This protein is upregulated in fibrotic diseases leading to additional collagen formation and deposition. In order to combat FUS upregulation, a new approach to blocking nuclear translocation has been developed using an FUS targeting peptide approach.


Licensing Contact

Janis Elsner

615.343.2430
Therapeutics

Non-Invasive Skin Cancer Detection using Raman Spectroscopy-OCT System (Portfolio)

Vanderbilt University researchers have designed a system for non-invasive discrimination between normal and cancerous skin lesions. The system combines the depth-resolving capabilities of OCT technique with Raman Spectroscopy's specificity of molecular chemistry. By linking both imagining techniques into a single detector arm, the complexity, cost, and size of previously reported RS-OCT instruments have been significantly improved. The combined instrument is capable of acquiring data sets that allow for more thorough assessment of a sample than existing optical techniques.


Licensing Contact

Ashok Choudhury

615.322.2503

Systems and Methods for Optical Stimulation of Neural Tissues (Portfolio)

Vanderbilt researchers have developed a novel technique for contactless simulation of the central nervous system.  This involves the use of infrared neural stimulation (INS) to evoke the observable action potentials from neurons of the central nervous system.  While infrared neural stimulation of the peripheral nervous system was accomplished almost a decade ago, this is the first technique for infrared stimulation of the central nervous system. This technology has been protected by a portfolio of issued patents.


Licensing Contact

Ashok Choudhury

615.322.2503

Prevention of Cytokine Induced Apoptosis In Intestinal Epithelial Cells By A Probiotic Bacterium

The present invention provides therapeutic and prophylactic compositions for use in treating and preventing disorders involved epithelial cell apoptosis, such as gastrointestinal disorders (e.g., inflammatory bowel disease, Crohn's disease or ulcerative colitis) in a subject, such as a human patient.


Licensing Contact

Janis Elsner

615.343.2430

Inventors

Brent Polk, Fang Yan
Therapeutics
Protein/Peptide
Gastrointestinal

MAESTRO: Non-Robotic Dexterous Laparoscopic Instrument with a Wrist providing seven degrees of freedom

Inventors at Vanderbilt University have developed a non-robotic dexterous laparoscopic manipulator with a wrist providing seven-degrees-of-freedom. The device has a novel user interface that intuitively maps motion of the surgeon's hands to the tool's "hands".


Licensing Contact

Ashok Choudhury

615.322.2503
Medical Devices

PosiSeat(TM): Assured Seating of Threaded Surgical Components

Vanderbilt presents an intraoperative device for taking the guesswork out of whether or not a threaded component is securely affixed to bone. This device is an anchor driver that automatically releases upon proper seating of the anchor on the bone of interest.


Licensing Contact

Taylor Jordan

615.936.7505

Portfolio of Image-Guidance and Organ Localization Technologies from the Lab of Professor Michael Miga

The focus of Dr. Miga's laboratory is on the development of new paradigms in detection, diagnosis, characterization, and treatment of disease through the integration of computational models into research and clinical practice.


Licensing Contact

Philip Swaney

615.322.1067

Image Guidance System for Breast Cancer Surgery

Vanderbilt researchers have developed an image guidance system that aims to reduce the revision rate for breast conserving surgeries through the use of intraoperative tumor location. The platform integrates MRI imaging, optical tracking, tracked ultrasound, and patient specific biomechanical models to provide a superior tumor localization end result.


Licensing Contact

Philip Swaney

615.322.1067