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TissueAb: An Unbiased In Vivo Screening Platform to Identify Tissue Targeting Antibodies

Application Cycle
February 2024

The TissueAb team seeks to enhance the technology that employs phage display libraries to identify tissues or cell type-specific antibodies (Ab) for targeted therapies. This technology will broadly apply to immune-oncology, autoimmunity, rare, and infectious diseases.

Awardee

Dr. Lauren Williamson is a translational immunologist developing next-generation antibody therapeutics for infectious diseases, cancer, and autoimmunity. At Vanderbilt, she leads efforts in antibody discovery and engineering, with a focus on monoclonal and bispecific formats, expression optimization, and phage display technologies. Her research has contributed to candidate therapeutics targeting Zika, Ebola, influenza, and other high-impact pathogens.

She is also the founder of TissueAb, a novel in vivo screening platform for identifying tissue-targeting antibodies with broad potential in precision medicine. Supported by Vanderbilt’s Innovation Catalyst Fund, the platform exemplifies Dr. Williamson’s focus on translating immunological advances into real-world therapeutic solutions.

Department