Many cancer cells evade critical DNA surveillance and maintenance by increasing the export — by the Exportin-1 (XPO1) nucleo-cytoplasmic transport protein — of nearly all major tumor suppressor proteins from the nucleus.
Researchers from Vanderbilt-Ingram Cancer Center (VICC) discovered a role for MYCN in triple-negative breast cancer (TNBC), a particularly aggressive form of the disease, and identified a potential intervention for further clinical investigation.
Robert Carnahan, PhD, associate professor of Pediatrics and Radiology and Radiological Sciences, has been appointed associate director of the Vanderbilt Vaccine Center.
For most social animals, even humans, the ability to distinguish friend versus foe can be a challenge that often can lead to knee-jerk aggression. But when it comes to ants getting aggressive, there’s a more sophisticated method to their madness.
