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Innovation Catalyst Fund

Awardees

The Awardees of the Innovation Catalyst Fund represent the pioneering spirit of our organization and embody our unwavering commitment to fostering innovation and cutting-edge research. We are proud to recognize and support these outstanding individuals and teams who are making significant strides in their respective fields and pushing the boundaries of scientific discovery. Below, you will find an overview of these remarkable Awardees, as we celebrate their achievements and contributions to advancing the frontiers of knowledge.

October 2024

Keivan G. Stassun, Ph.D.

Stevenson Professor of Physics and Astronomy

Learning with Optimal Guidance for Autistic Navigators (LOGAN) Virtual Driving Instruction System

SANDI supports neurodiverse individuals, particularly those on the autism spectrum, in achieving driving independence by addressing barriers like anxiety and sensory overload through structured, repetitive learning. This innovative simulator enhances confidence, provides greater accessibility to driving skills, and promotes long-term social and economic inclusion.

John P Wikswo

University Distinguished Professor of Biomedical Engineering, Molecular Physiology and Biophysics, and Physics

Accelerating the Development and Commercialization of a Robot Scientist/Self-Driving Biological Laboratory

This project seeks to develop scalable, 1,000-channel CAPCAS microbioreactor systems to accelerate AI/ML-driven advancements in cell-culture control for biologically produced pharmaceuticals and industrial chemicals. The outcome will enable more efficient cell-line identification, media optimization, and bioreactor control, ultimately transforming the BioPharma industry by improving automation and scaling of cell-culture studies.

Jad Abumrad

Distinguished Research Professor, Cinema & Media Arts

Waiting Room Stories, Product Development Phase

This initiative aims to transform the hospital waiting room experience by providing patients with a curated playlist of stories, offering comfort and connection during a typically isolating and stressful time. The project will develop a user-friendly digital platform to deliver these stories and potentially allow patients to contribute their own, with plans for wider implementation across hospitals.

Panambur Bhandari, MD

Assistant Professor of Plastic Surgery

Intrinsic Glove: Saving Traumatized Hands

The team is developing the Intrinsic Glove, a semi-rigid, flexible orthosis designed to improve hand trauma management by promoting safe positioning, early motion, and compression. This innovative glove enhances patient care and provider efficiency by enabling quick, effective positioning and reducing setup time significantly.

Lisa Fazio

Associate Professor of Psychology and Human Development

Developing a Novel Platform for Social Science Research Using LLM Persona-Agents

The team is developing an automated, text-based platform with customizable persona-agents to simulate social interactions, enabling research on how conversations influence beliefs, disinformation, and radicalization in chat-based environments.

Scott A Guelcher, Ph.D.

Professor of Chemical and Biomolecular Engineering

Preclinical Testing of Resorbable Surgical Mesh

This proposal aims to develop poly(thioketal thiourethane) (PTKTUR) elastomers for surgical mesh that support tissue regeneration and degrade in response to cell-secreted reactive oxygen species, with tunable mechanical properties matching patient biology.

Eric P. Skaar, Ph.D.

Director, Institute for Infection, Immunology and Inflammation (VI4)

A Stabilizing Agent That Enhances the Resistance of Probiotics and Recombinant Enzymes to Heat and Desiccation

This technology will use the bacterial hydrophilin DtpA to enhance the stability and viability of probiotics and enzymes under extreme conditions, improving strain diversity, bacterial recovery, and enzyme protection for microbiome-based therapeutics.

June 2024

Joshua Caldwell

Professor of Mechanical Engineering

Expanding Sensorium Technological Labs Core Technologies into the Health Care Industry

The team is developing Tamm polariton multi-frequency thermal emitters and filters for enhanced gas sensing, with applications in semiconductor monitoring and healthcare, such as breath analysis for early disease detection, based on AI-driven design from the Caldwell Lab at Vanderbilt.

Ellen Goldbring

Patricia and Rodes Hart Chair

Research Concierge: A Tool to Connect Faculty and Staff with the Resources Needed to Increase Research Impact

The team is developing Peabody Research Concierge (PRC), a conversational AI designed to enhance the matching process between Vanderbilt faculty and relevant research funding opportunities, optimizing resource discovery through AI-driven insights based on individual expertise.

Elisa J. Gordon, Ph.D.

Professor of Surgery

Developing a LLM-based Chatbot to Scale Returning Genetic Test Results

The team will create a patient-centered, AI-powered chatbot to explain APOL1 genetic test results, guide kidney health behaviors, and reduce anxiety, addressing the national shortage of genetic counselors and improving the communication of genetic test results for kidney disease risk.

Lisa H. Lancaster, M.D.

Professor, Department of Medicine

Auto titration Oxygen Therapy Device with Real-Time Monitoring: Improving Accuracy of Dosing Oxygen and Quality of Life for Patients

The team aims to develop a novel oxygen regulator with an auto-titration algorithm that uses SpO2 and activity data from wearables to automatically adjust oxygen flow rates, improving dosing accuracy and patient health outcomes. This closed-loop system offers personalized oxygen therapy, eliminating the need for manual adjustments and ensuring continuous, optimal oxygen levels.

Rei Ukita, Ph.D.

Research Assistant Professor Department of Cardiac Surgery

Wearable Extracorporeal Membrane Oxygenation System for Safer Patient Ambulation

The team aims to create a portable extracorporeal life support system that integrates a blood pump, oxygenator, and user interface, enabling ambulatory ECMO use to improve patient mobilization and outcomes, particularly for those awaiting lung transplants.

Lauren Williamson, Ph.D.

Research Assistant Professor

TissueAb: An Unbiased in Vivo Screening Platform to Identify Tissue Targeting Antibodies

The team will develop a platform using phage display libraries to identify antibody variants specific to targeted tissues, enhancing the development of biologics for immune-oncology, autoimmunity, and other diseases through in vivo screening and next-generation sequencing.

February 2024

Matthew D. Bacchetta, M.D.

Professor of Cardiac Surgery, Thoracic Surgery, and Biomedical Engineering

Dynamic Organ Storage System

The team is advancing a portable Dynamic Organ Storage System (DOSS) for organ transports. This system maintains and monitors a uniform organ temperature and ensures a steady supply of essential energy substrates, thus preventing cellular damage and temperature gradients.

Michael Golinko, M.D.

Delta Dental of TN Smile 180 Foundation Director of the Cleft & Craniofacial Program

Image Assist: Implementing the Standard for Mobile Clinical Photography

Image Assist is a unique clinical photography tool that uses dynamic digital frames to take patient pictures accurately as per ASPS/PSF clinical photography guidelines and subtract noise. This technology was inspired by the concept of mobile check deposit.

Tina M. Iverson, Ph. D.

Professor, Department of Pharmacology

Inhibition of Bacterial Chemotaxis as an Antibiotic Potentiator

The team aims to develop a molecule that inhibits bacterial movement during UTI infection, thus preventing bacteria from escaping antibiotics and forming recurrent infections. This strategy could significantly reduce recurrent, resistant infections, particularly in UTIs.

Stacy D. Sherrod

Research Associate Professor of Chemistry

Molecular Omics for Personalized Skincare

An innovative skin intelligence platform that uses skin mass spectrometry (MS) data to analyze the detailed molecular makeup of an individual’s skin and make skin product recommendations accordingly.

Lauren Williamson, Ph.D.

Research Assistant Professor

TissueAb: An Unbiased In Vivo Screening Platform to Identify Tissue Targeting Antibodies

The TissueAb team seeks to enhance the technology that employs phage display libraries to identify tissues or cell type-specific antibodies (Ab) for targeted therapies. This technology will broadly apply to immune-oncology, autoimmunity, rare, and infectious diseases.

Ellen T. Armor

E. Rhodes and Leona B. Carpenter Chair in Religion, Gender and Sexuality

Courageous Voices in Action: The LGBTQIA+ Advocacy Project

The Courageous Voices in Action (CVA) seeks to develop a scalable curriculum focused on moral courage, leadership, and cultural-religious literacy that produces knowledgeable leaders who can challenge injustice and support LGBTQIA+ thriving.

 

October 2023

Amy E. Booth

Professor of Psychology and Human Development

Advancing the Development of AIDA, an Artificially-Intelligent Dialogic Reading Aid.

The team seeks to address the societal imperative of literacy by developing a technology that will facilitate dialogue reading between caregivers and young children. These interventions involve encouraging children to engage in conversations around books, rather than just passively listening.

 

Blythe Corbett, Ph.D.

Expanding SENSE Theatre to Youth with Autism Spectrum Disorder and Intellectual Disability.

SENSE Theatre is a unique intervention research program for youth, 10-16 years of age, with autism spectrum disorder (ASD). It is a performance-based intervention targeting social skills that includes trained peer actors and theatretechniques.

Scott Crossley

Professor, Department of Special Education

Proof of concept validation and data generation for intelligent Texts for Enhanced Lifelong Learning (iTELL).

The iTELL framework restructures text-based learning materials into individual web apps where students can read text content, participate in interactive exercises, and watch educational videos. 

Abhishek Dubey

Associate Professor of Computer Science

Mobius, Inc: Last mile Freight Optimization for Heterogenous Fleets.

The project aims to further develop a technology around optimizing the routing and charging of mixed-fleet transportation and last-mile freight resources (e.g., buses and trucks).

Daniel Fabbri, Ph.D.

Assistant Professor of Biomedical Informatics

DAGCAP: Democratized, AI-Guided Chart Abstraction Platform.

DAGCAP aims to create a streamlined and automated curation system that mitigates challenges associated with medical charting. Increases in the quality of curation would drastically expand research, clinical, and operational capabilities across oncology care and research.

Alexander Langerman, M.D., S.M.

Associate Professor of Otolaryngology-Head and Neck Surgery

GownCard Perioperative Workflow App.

GownCard is an internally-developed, app-based surgical team information management system used by nurses, scrub techs, and surgeons to eliminate perioperative inefficiencies.

 

Ethan Lippmann

Associate Professor of Chemical and Biomolecular Engineering

Novel Hydrogel to Improve and Restore Blood Flow to Bone Tissues Through Activation of Arteriogenesis.

This injectable gelatin-based hydrogel promotes the growth of large blood vessels in a spatially controlled manner to restore blood flow to inadequately supplied areas. Because this hydrogel is formulated without encapsulated growth factors or cells, it can be easily translated to clinical applications.

 

Megan Salwei, Ph.D.

Assistant Professor Departments of Anesthesiology and Biomedical Informatics

Personalized training on deep inspiration breath hold (DIBH) to improve radiation therapy outcomes in breast cancer patients.

The project aims to develop a system to support patient execution of DIBH. The system will feed, real-time, to software driving a VR display to provide visual feedback to patients on their DIBH.