Breakthrough Approaches in Neuropathic Pain Relief

The "Breakthrough Approaches in Neuropathic Pain Relief" initiative focuses on discovering novel therapeutic and diagnostic technologies to address neuropathic pain. Projects should improve patient outcomes and demonstrate a clear path to clinical translation.

What we're looking for: 

Seeking innovative topical and systemic solutions for neuropathic pain that can be developed into effective, consumer-friendly over-the-counter (OTC) treatments, leveraging emerging science and holistic approaches.

Open to novel delivery methods that enhance the efficacy or tolerability of existing active compounds, such as improving the performance of ingredients like capsaicin.

Must-have requirements are:

• Preliminary evidence or scientific rationale indicating potential efficacy
• Designed or adaptable for consumer-friendly, over-the-counter (OTC) use

Nice-to-have requirements are:

• Demonstrated mechanism of action targeting neuropathic pain symptoms
• Offers flexibility for personalized or adjustable dosing/use
• Supported by early user or patient feedback indicating acceptability
• Avoids reliance on controlled substances or heavily regulated ingredients

Out of scope:

• Prescription-only drugs (Rx), unless supported by a clear path to OTC conversion
• Cosmetic products lacking scientific evidence or therapeutic intent

Please note: Faculty and researchers interested in applying for these opportunities based on technologies developed or disclosed at Vanderbilt must submit their proposals through the CTTC.