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Defining biomarker fingerprints of optimal micronutrient and health states

A global consumer health company seeks validated biomarker panels and omics/multi-omics assays that can quantify micronutrient status and link it to health outcomes beyond basic deficiency prevention, ultimately supporting evidence for optimal intake levels.

Overview

  • Collaborative opportunity with a global consumer health company specializing in over-the-counter products
  • Focus on developing validated multi-analyte panels and omics assays for micronutrient status
  • Interest in biomarker profiles that distinguish baseline sufficiency from enhanced health states
  • Strategic goal of testing whether above-RDA intakes can shift individuals to improved health profile

Priority Areas

  • Multi-analyte Panels: Biomarker panels capturing combined micronutrient status
  • Omics Approaches: Methods linked to cognitive health, immunity, mobility, gut health, healthy aging, or weight management
  • Multi-omics Signatures: Metabolomic/proteomic signatures connected to key health outcomes
  • Composite Biomarkers: Fingerprints distinguishing sufficiency versus enhanced health states
  • Validation Studies: Biomarker shifts under above-RDA nutrient intakes
  • Longitudinal Data: Connections between intake, biomarkers, and health improvements
  • Reference Ranges: Measures beyond deficiency linked to weight/metabolic outcomes

Eligibility & Requirements

  • Clear link to micronutrient status and/or specified health outcomes
  • Measures biomarker patterns or profiles (≥5 micronutrients), not single markers in isolation
  • Evidence supporting interpretable profiles tied to micronutrient status and/or health outcomes
  • Solutions must not be exploratory or mechanistic-only data
  • High-cost technologies (>$200/sample) are out of scope

 

Please note: Full RFP is attached in the "More Information" section of this page. Faculty and researchers interested in applying for these opportunities based on technologies developed or disclosed at Vanderbilt must submit their proposals through the CTTC.