Background
Lipid oxidation is a leading cause of food spoilage, resulting in significant product rejection, waste, and consumer dissatisfaction. Hexanal, a volatile organic compound formed during lipid oxidation, is a key indicator of this spoilage and plays a critical role in monitoring food quality. Unfortunately, current methods for testing hexanal are often time-consuming, inefficient, and not suitable for use at the manufacturing plant level. Our current setup, for instance, depends on highly sensitive equipment that requires a skilled technician for maintenance, takes anywhere from half a day to a full day to complete testing, and requires several more hours to generate results. These challenges directly impact productivity, increase operational costs, and undermine customer trust in product quality.
What we're looking for
We are looking for innovative, economical, and effective technologies capable of accurately and efficiently quantifying hexanal levels in dry materials such as animal protein. By implementing the potential cutting-edge solutions, our goal is to improve quality control efficiency for both incoming raw materials and products, ensuring product quality and minimizing waste. The ideal solution should provide precise hexanal quantification with minimal preparation and quick analysis, while being affordable and user-friendly for implementation at the manufacturing plant level.
Solutions of interest include:
- Atmospheric pressure chemical ionization mass spectrometry (APCI-MS)
- Ion mobility spectrometry (IMS)-hyphenated technologies (e.g., GC-IMS
- Selected ion flow tube mass spectrometry (SIFT-MS)
- Proton transfer reaction mass spectrometry (PTR-MS)
- Portable GC-MS or HPLC
- Direct analysis in real time (DART-MS)
- Ion mobility mass spectrometry (IMS)
- Technologies that quantify other key lipid oxidation derivatives for quality control
Our must-have requirements are:
Measures hexanal in dry animal proteins, ranging from 3 -10 ppm, with a Limit of Quantification (LOQ) of ≤ 3.0 ppm
Supports testing of at least 10 samples daily
Completes the measurement in 60 mins or less, from sample preparation to final result
Cost-effective, ideally within $50K-100k USD for equipment and consumable costs below $30 USD per test
Our nice-to-have's are:
- Achieves a Limit of Quantification (LOQ) of ≤ 1.0 ppm
- Consumables ongoing cost < $15 USD per test
- Accurately quantifies hexanal in other dry materials
- Supports testing of at least 30 samples daily
- Does not require the use of solvent or gas besides air or nitrogen
- Required daily preventive maintenance ≤ 15 mins
- Commercially available for immediate deployment
Email Swapneeta Date, CTTC Assistant Director of Life Sciences Collaborations, at Swapneeta.Date@Vanderbilt.edu for more information.