ThermoFisher Scientific - Research Interest Areas

Vanderbilt Labs

 

 

Protein Detection & Quantification

Improvements in Western Blot productivity and imaging; highly-multiplexed immunoassays (>200 markers at once); new membranes; stain-free gels; next-gen electrophoresis; ELISA automation

Cell & Protein Analysis Consumables

Protein sample prep solutions; reagents and sample prep solutions for mass spectrometry analysis; fluorescent probes for measuring cell health & content; functional flow cytometry reagents; fluorescent assays run on Qubit platform; low-cost cell counting technologies; novel bioconjugation technologies

Cell Analysis Instruments

3D imaging data analysis solutions; novel label-free technologies (optical included); cell sorting and sample prep solutions for flow cytometry

Bio-Production

Cell engineering for improved titer, stability, and quality; technologies for improved culture yield and quality across a broad range of cell types; media and bioprocessing for cell and gene therapy; analysis of recombinant protein quality; rapid bioburden technology; bioprocess data analytics; technologies for new biotherapeutic modalities; technologies for process intensification; continuous bioprocessing; single-use technologies; process skid and column technologies; bioprocess filtration.

Laboratory Chemicals

Reagents used in chemical synthesis including building blocks; organic reagents; green solvents; inorganics and catalysts; specialized compounds used in the areas of electronics; batteries; nanotechnology; compound libraries for screening such as high-throughput or fragment screening libraries

Laboratory Products

High purity/low extractables & leachables resin/plastic/polymer; injection blow molding; surface treatment processes to block migration from plastic to sample; refrigeration; cryopreservation systems; cold storage sample preparation; devices and methods for cold storage of pharmaceutical, vaccine, blood, enzyme, and plasma; precision temperature control; electrodes and sensor technologies including solid state technologies; functionalized materials such as 3D-graphene for water purification applications; magnetocaloric technology for environmental chambers applications; novel separation technologies; alternative cooling systems; low speed temperature control, direct sample temperature measurement; low noise emission centrifuge; aerodynamic rotor design; hands-free operation; separation/centrifuge consumables (tubes, bottles, accessories);measuring sensor technology; advances in vibration-free/hands-free closure technologies; noise reduction technologies and low noise motor designs; advances in HEPA filtration design technologies; novel bioreactor designs and control software systems

Advanced Cell Models

Disease models; improved iPSC and adult stem cell workflows, including reprogramming, differentiation, and characterization; 3D cell culture and analysis, growth factors; 3Dculture cell line; cell banks, scale-up technologies; 3D cell culture plastics; organoid and spheroid cell culture; animal-origin free cell culture components; surrogates for serum or albumin in cell culture media; workflow simplification and automation instruments/devices; iPSC maturation

Transfection and Protein Expression

Expression platform; proteins for better crystallizations, protein labelling; expression scale up; new host cell line, including mammalian and non-mammalian line; growth media for host cell line; post-translation modification; structural analysis tools; protein isolation; macromolecules delivery system

Gene Editing

CRISPR technology for efficient knock in/out; CRISPR-related enzymes; labeling protein; RNAi technology; in-vitro transcription tools; RNA expression; gene editing software

Cell and Gene Therapy

T cell therapy; cancer vaccine; gene delivery system; lentivirus, adeno-associated virus vector; technologies for physiologically relevant cell models; instruments and devices to simplify cell culture and cell processing; cell culture plastics; instruments and systems to support closed cell processing; novel methods for cell isolation and activation; viral and non-viral engineering tools; culture and cryo-preservation media for immune and stem cells; novel characterization assays and analytics

Food safety and animal health

Food and water testing for pathogens and contaminants using ELISA, qPCR, or next-generation sequencing (NGS)

Molecular Biology

Temperature-sensitive polymerases; restriction enzymes; competent cells and stabilization; PCR plastics; RNA/DNA sample preparation

NGS

Novel sequencing technologies, research applications and workflows; AI/ML bioinformatics tools; single-cell sequencing

Genetic Analysis

Extraction, purification, and rapid detection; instruments and reagents for PCR, RT-PCR, and dPCR; human identification and forensic DNA analysis; novel biomarkers for sample deconvolution; non-invasive prenatal testing; fetal cell isolation; DNA-free reagents; novel microarray fabrication technologies; novel capillary electrophoresis polymers and reagents; AI/ML tools for data processing, analysis, and visualization

Product Design

User interface improvements; packaging innovations; reagentstabilization technologies; green technologies; single-tube formulations

Sample Prep

Sample collection tools, cell-free DNA sample prep, T-cell activation technologies, exosome isolation from blood, urine, plasma and serum or immunoprecipitation, nucleic acid analysis from raw samples