Browse Technologies

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Molecular Image Fusion: Cross-Modality Modeling and Prediction Software for Molecular Imaging

A research team at Vanderbilt University Mass Spectrometry Research Center has developed the Molecular Image Fusion software system, that by fusing spatial correspondence between histology and imaging mass spectrometry (IMS) measurements and cross-modality modeling, can predict ion distributions in tissue at spatial resolutions that exceed their acquisition resolution. The prediction resolution can even exceed the highest spatial resolution at which IMS can be physically measured. This software has been successfully tested on different IMS datasets and can be extended to other imaging modalities like MRI, PET, CT, profilometry, ion mobility spectroscopy, and different forms of microscopy.


Mouse Anti-Rabbit Rab25 Monoclonal Antibody

This research targets Rab25.


Licensing Contact

Jody Hankins
jody.hankins@vanderbilt.edu
615.322.5907

Inventors

James Goldenring
Research Tools
Antibody
Oncology

Screening Assay for Molecules That Alter Cell Cycle Rhythm

This research targets Cell Cycle.


Licensing Contact

Karen Rufus
karen.rufus@vanderbilt.edu
615.322.4295
Research Tools
Assays/Screening
Oncology Research Reagent

Mice with Inducible Cre-ERt Replacing Cytokeratin 19 Coding Region

This research targets CK19.


Licensing Contact

Taylor Jordan
taylor.jordan@vanderbilt.edu
615.936.7505

Inventors

Guoqiang Gu, Anna Means
Research Tools
Animal Model
Oncology

MEF Cell Line Derived From Histone Deacetylase-3 Conditiontal Knockout Mice

This research targets HDAC-3.


Licensing Contact

Jody Hankins
jody.hankins@vanderbilt.edu
615.322.5907

Inventors

Scott Hiebert
Research Tools
Cell Line
Oncology

Human Monoclonal Antibodies to Infectious Diseases

Using human B cell hybridoma creation, and antibody engineering technologies, Dr. James E Crowe Jr.'s laboratory has developed an array of antibodies from full length human antibodies to Fab fragments and diabodies. Many of these antibodies are ready for a cooperate partner who can further develop these antibodies into biologic herapeutics. The table below is a sample of the antibodies they are currently researching and have available. In addition to these areas of research, Dr. Crowe is actively seeking collaborative opportunities to identify new interesting targets for future antibody engineering projects.


Potassium Voltage-Gated Channel Subfamily E Member 1 Null Mice

This research targets minK


Licensing Contact

Jody Hankins
jody.hankins@vanderbilt.edu
615.322.5907
Research Tools
Animal Model
Cardiovascular

Human sodium channel beta 1 and beta 2 subunits

HEK-293 cell line stably expressing human sodium channel beta 1 and beta 2 subunits. This cell line expresses the two human sodium channel accessory subunits needed for robust expression of sodium channel protein.


Licensing Contact

Karen Rufus
karen.rufus@vanderbilt.edu
615.322.4295
Research Tools
Cell Line

Slc5a7 (choline transporter, CHT) BAC Transgenic Mouse

A Bacterial Artificial Chromosome (BAC) containing the mouseSlc5a7 gene was used to make transgenic mice. Mice show elevated choline transporter and acetylcholine levels and increased treadmill endurance.


Licensing Contact

Karen Rufus
karen.rufus@vanderbilt.edu
615.322.4295

Inventors

Randy Blakely
Research Tools
Animal Model