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PIQASO: A rigid phantom for comprehensive end-to-end evaluation of online adaptive radiotherapy systems

There is currently no radiotherapy phantom capable of quantitatively assessing all components of an online adaptive radiotherapy (online ART) system in a comprehensive end-to-end test.Represented here is a novel, rigid phantom that can simultaneously evaluate an online ART system's image acquisition, deformable image registration, contour propagation, plan re-optimization, dose calculation, and beam delivery in a single process that is robust, quantitative, and convenient.


Licensing Contact

Masood Machingal

615.343.3548

Inexpensive Disposable Hydro-Jet Capsule Robot for Gastric Cancer Screening in Low-Income Countries

Gastric cancer is the second leading cause of cancer death worldwide. While screening programs have had a tremendous impact on reducing mortality, the majority of cases occur in low and middle-income countries (LMIC). Typically, screening for gastric and esophageal cancer is performed using a flexible endoscope; however, endoscopy resources for these settings are traditionally limited. With the development of an inexpensive, disposable system by Vanderbilt researchers, gastroscopy and colonoscopy can be facilitated in areas hampered by a lack of access to the appropriate means.


Licensing Contact

Masood Machingal

615.343.3548

No-touch Breast Implant Placement Device

Vanderbilt researchers have developed a breast implant device that minimizes potential contaminants during surgery by requiring no contact between the surgeon and the implant during insertion.


Licensing Contact

Philip Swaney

615.322.1067
Medical Devices
Surgery

Surgical Guide for Intraoral Vertical Ramus Osteotomy

Vanderbilt researchers have developed a novel surgical guide for intraoral vertical ramus osteotomy (IVRO) that helps to preserve the proximal segment medial pterygoid attachment and avoid injury to the inferior alveolar neurovascular bundle during the procedure.


Licensing Contact

Philip Swaney

615.322.1067
Medical Devices

Method and System for Automating Oxygen Monitoring and Dosing in Real Time for Patient on Oxygen Therapy

Vanderbilt researcher, Lisa Lancaster, MD, has developed a novel device to monitor the flow as well as adjust actively the levels of oxygen that pass to a patient suffering from Idiopathic Pulmonary Fibrosis or other causes of hypoxic lung disease. Standing out of the pack, this device ensures that patients exerting themselves are given enough oxygen while actively reducing the dosage, to prevent further damage, when the same patient is resting.


Licensing Contact

Masood Machingal

615.343.3548

Inventors

Lisa Lancaster
Medical Devices
Pulmonary/Respiratory

Bioresorbable RF Coils for Post-Surgical Monitoring by MRI

Vanderbilt researchers have developed bioresorbable RF coils to improve the signal-to-noise ratio (SNR) for use in post-surgical monitoring.


Licensing Contact

Chris Harris

615.343.4433

Inventors

Mark Does, John Rogers

Molecular Image Fusion: Cross-Modality Modeling and Prediction Software for Molecular Imaging

A research team at Vanderbilt University Mass Spectrometry Research Center has developed the Molecular Image Fusion software system, that by fusing spatial correspondence between histology and imaging mass spectrometry (IMS) measurements and cross-modality modeling, can predict ion distributions in tissue at spatial resolutions that exceed their acquisition resolution. The prediction resolution can even exceed the highest spatial resolution at which IMS can be physically measured. This software has been successfully tested on different IMS datasets and can be extended to other imaging modalities like MRI, PET, CT, profilometry, ion mobility spectroscopy, and different forms of microscopy.


Licensing Contact

Karen Rufus

615.322.4295

Self-Decoupled RF Coils for Optimized Magnetic Resonance Imaging

Magnetic resonance imaging (MRI) is one of the most important and versatile tools in the repertoire of diagnostics and medical imaging. Vanderbilt researchers have developed a novel, geometry independent, self-decoupling radiofrequency (RF) coil design that will allow MRI machines to generate images at a faster rate and with greater image quality.


Licensing Contact

Philip Swaney

615.322.1067

Advanced Ultrasound Imaging for Kidney Stone Detection

The standard for kidney stone detection is through the use of computed tomography (CT). However, CT is expensive and delivers harmful ionizing radiation into the body. Ultrasound would be the ideal way to detect kidney stones except that it performs poorly in detecting and accurately sizing stones. Vanderbilt researchers inventors have developed a technique that is able to separate hard, mineralized material (i.e kidney stones) from soft tissue in a way that is both cheaper and safer than CT and performs better than conventional ultrasound imaging.


Licensing Contact

Masood Machingal

615.343.3548

Assessment of Right Ventricular Function Using Contrast Echocardiography

Vanderbilt Medical Center researchers have developed a non-invasive and reproducible method of assessing right-ventricular function using contrast-echocardiography. The right-ventricular transit time (RVTT) measures the time needed for echocardiographic contrast to travel from the RV to the bifurcation of the main pulmonary artery. Coupled with the pulmonary transit time (PTT), the time needed for contrast to traverse the entire pulmonary circulation, RVTT is part of a family of diagnostic parameters that can report on RV-specific performance as well as the RV's function relative to that of the pulmonary circuit as a whole.


Licensing Contact

Chris Harris

615.343.4433