Cardiovascular

Displaying 1 - 10 of 12


Novel anti-platelet therapy for treatment of thrombosis, cardiovascular disease, and cerebrovascular injury

One of the leading causes of deaths in developed countries is related to thromboembolism. PAR-4 (protease activated receptor-4) is one of two receptors on the human platelet that respond to thrombin, the central enzyme of coagulation.  Researchers here at Vanderbilt University have developed novel antagonists of PAR-4 that could be beneficial for patients allowing for normal hemostasis during treatment for thrombotic events.


Licensing Contact

Mike Villalobos

615.322.6751
Therapeutics
Cardiovascular

pECHO: Easy to Use Smartphone App for Assisting in Transesophageal Echocardiography Exam

Transesophageal echocardiography (TEE) is a test that uses high-frequency sound waves to create images of the heart. It provides more detail that a standard echocardiogram. Vanderbilt researchers have created a software that creates an easy to follow, step-by-step procedure for a transesophageal echocardiography exam.


Licensing Contact

Masood Machingal

615.343.3548

Long-Lasting and Self-Sustaining Cell Therapy System

Researchers at Vanderbilt have created a novel drug delivery system using two distinct T-cell populations that interact to promote engraftment and persistence in pre-clinical models, increasing the efficacy of T-cell therapies. Furthermore, "booster" treatments can be administered months after the first dose to produce an expansion of antigen specific T cells. These advantages result in longer-term therapeutic efficacy and could reduce the number of treatments required. This system also represents a viable self-renewing platform for the delivery of biologic drugs in patients who would otherwise require frequent administration.


Licensing Contact

Cameron Sargent

615.322.5907

Automated Inflatable Binder to Counter the Effects of Orthostatic Hypotension

Vanderbilt scientists have developed an automated inflatable abdominal binder that can detect when a patient moves from a prone or sitting positon to a standing position and automatically apply a sustained servo-controlled compression pressure in order to counter the effects of OH. The binder is as effective as conventional drug therapy in controlling OH, without subjecting patients to potentially harmful side effects and interactions with other medications.


Licensing Contact

Taylor Jordan

615.936.7505
Medical Devices
Cardiovascular

Luciferase Reporter System for Viral Detection in Vitro and in Vivo

This research targets Respiratory Syncytial Virus.


Licensing Contact

Taylor Jordan

615.936.7505

Endothieal Nitric Oxide Synthase Null Mice (db/db background)

This research targets eNOS.


Licensing Contact

Karen Rufus

615.322.4295

Inventors

Raymond Harris
Research Tools
Cardiovascular
Animal Model

Mouse Model for Cardiovascular/Autonomic Disorders

This research targets CHT.


Licensing Contact

Karen Rufus

615.322.4295
Research Tools
Animal Model

Floxed Prostaglandin D2 Receptor Alleles

This research targets DP1.


Licensing Contact

Karen Rufus

615.322.4295

Inventors

Richard Breyer
Research Tools
Animal Model

Purified Bovine cAMP and cGMP Dependant Protein Kinases

This research targets PKA, PKG.


Licensing Contact

Karen Rufus

615.322.4295

Inventors

Jackie Corbin
Research Tools
Cardiovascular
Protein/Peptide

EP4 Transgenic Mice

EP4 Transgenic Mice are part of the Vanderbilt Research Tools Catalog.


Licensing Contact

Karen Rufus

615.322.4295
Research Tools
Animal Model